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2020, Number 4

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Rev Ciencias Médicas 2020; 24 (4)

Prognostic factors of mortality rate in patients with spontaneous intracerebral hemorrhage

Rodríguez-Venegas EC, Hernández-García OL, Denis-Piedra DA, Cabrera-Nicó A, Valdés-Blanco M
Full text How to cite this article

Language: Spanish
References: 17
Page: 1-13
PDF size: 395.96 Kb.


Key words:

intracerebral hemorrhage, Glasgow coma scale, mortality, prognostic factor.

ABSTRACT

Introduction: spontaneous intracerebral hemorrhage (ICH) is considered, among all strokes, the one having the most devastating effect, the estimated mortality rate per month ranges between 35 and 52 %.
Objective: to determine the factors that influence 30-day mortality rate in patients with Spontaneous Intracerebral Hemorrhage.
Methods: a cross-sectional, analytical, observational study conducted at Dr. Carlos Juan Finlay Military Hospital over a period of 3 years (2017 to 2019). The target group comprised 75 patients. Demographic, clinical and tomographic variables were studied. Descriptive statistics was applied: absolute and relative frequency, arithmetic mean and standard deviation; along with inferential statistics: logistic regression using the Odds Ratio with a 95 % confidence interval, for a positive significance on p <0.05.
Results: the age group from 48 to 75 years prevailed with 45 patients (60 %), male sex 44 patients (58. 7%), and white race 33 (44 %). Hypertension predominated as the main antecedent in 61 patients (81. 3 %). Significantly positive results were obtained for ages over 80 (p = 0,001); the severe state according to Glasgow Coma Scale (p = 0,005); the presence of ventricular extension (p = 0,001) and treatment with oral anticoagulants (p = 0.023).
Conclusions: intracerebral hemorrhage is evidence for extensive mortality rates. People over 80 years old, treated with oral anticoagulants have a higher risk of death due to this entity. Ventricular extension and a low score on the Glasgow Coma Scale worsen the prognosis.


REFERENCES

  1. Macías Ruíz V, Cordero Pérez MB, Vásquez Cedeño D, Saltos Mata F. Factores Asociados a la Mortalidad de la Hemorragia Cerebral Intraparenquimatosa Espontánea en Pacientes Mayores de 50 Años de Edad que Acudieron al Hospital Teodoro Maldonado Carbo Durante el Año 2017. Rev. Ecuat. Neurol. [internet] 2019 [citado 13/12/2019]; 28 (1): 10-15. Disponible en: Disponible en: http://scielo.senescyt.gob.ec/scielo.php?script=sci_abstract&pid=S2631-25812019000100010&lng=es&nrm=iso

  2. Castillo J, Luna A, Rodríguez-Yáñez M, Ugarriza I, Zarranz JJ. Enfermedades vasculares cerebrales. En: Zarranz JJ. Neurología Sexta edición. Elsevier: España, [internet] 2018 [citado 13/12/2019]. Disponible en: Disponible en: https://inspectioncopy.elsevier.com/6/es/book/details/9788491130710

  3. Suárez-Quesada A, Álvarez-Aliaga A, López-Espinosa E, Bárzaga-Morell S, Santisteban-García A. Pronóstico de muerte en pacientes con hemorragia intracerebral supratentorial espontánea. Revista Finlay [revista en Internet]. 2016 [citado 11/12/2019]; 6(1): [aprox. 8 p.]. Disponible en: Disponible en: http://revfinlay.sld.cu/index.php/finlay/article/view/408

  4. Ropper AH, Samuels MA. Enfermedades Cerebrovasculares. En: Adams y Victor: Principios de Neurología. Parte IV. Capítulo 35. Décima Edición. McGraw-Hill: México; [internet] 2016 [citado 13/12/2019]. Disponible en: Disponible en: https://es.slideshare.net/kevinarmijosm/adams-victor-principiosneurologiafororinconmedicotk

  5. Chen S, Zhao B, Wang W, Shi L, Cesar Reis C, Zhang J. Predictors of hematoma expansion predictors after intracerebral hemorrhage. Oncotarget, [internet] 2017 [citado 13/12/2019]; 8(51): 89348-63. Disponible en: Disponible en: https://www.ncbi.nlm.nih.gov/m/pubmed/29179524&sa=U&ved=2ahUKEwi1-pat_PDoAhWNmuAKHcAgAvQQFjABegQIABAB&usg=AOvVaw0jYGj6VBAa_ki0KDf8Ys64

  6. Øie LR, Mattis A, Madsbu, Solheim O, Asgeir S, Jakola, Giannadakis C, Vorhaug A, et al. Functional outcome and survival following spontaneous intracerebral hemorrhage: A retrospective population‐based study. Brain and Behavior. [internet] 2018 [citado 13/12/2019]; 8: e01113. Disponible en: Disponible en: https://dx.doi.org/10.1002/brb3.1113

  7. Green L, Tan J, Morris JK, Alikhan R, Curry R, Everington T, et al. A three-year prospective study of the presentation and clinical outcomes of major bleeding episodes associated with oral anticoagulant use in the UK (ORANGE study). Haematol [internet] 2018 [citado 13/12/2019]; 103 (4): 738-745. Disponible en: Disponible en: http://www.doi:10.3324/haematol.2017.182220

  8. Hemphill JC, Bonovich DC, Besmertis L, Manley GT, Johnston SC. The ICH score: a simple, reliable grading scale for intracerebral hemorrhage. Stroke. [internet] 2001 [citado 13/12/2019]; 32: 891-7. Disponible en: Disponible en: https://www.ncbi.nlm.nih.gov/m/pubmed/11283388&sa=U&ved=2ahUKEwiZ_LzK_PDoAhXCmeAKHcdXA0AQFjACegQICBAB&usg=AOvVaw0tAAlvTgKZn7qkHyTyku_N

  9. Méndez Fleitas L, Carmona Denis Y, Moreno Peña LE, Escalona Robaina CR, Ortega Peñate JA. Caracterización clínica de la hemorragia intracerebral en pacientes ingresados en Hospital Faustino Pérez. 2012-2013. Rev Méd Electrón [Internet]. 2019 Ene-Feb [citado: 12/12/2019]; 41(1). Disponible en: Disponible en: http://www.revmedicaelectronica.sld.cu/index.php/rme/article/view/2985/4172

  10. Clarke JL, Johnston SC, Farrant M, Bernstein R, Tong D, Hemphill JC 3rd. External validation of the ICH score. Neurocrit Care [internet] 2004 [citado 13/12/2019]; 1(1): 53-60. Disponible en: Disponible en: http://neurocriticalcare.pbworks.com/f/ICH%2BScore%2Bvalidation%2Bpaper.pdf&sa=U&ved=2ahUKEwjU1JXw_PDoAhWLUt8KHecyC5QQFjAFegQIAxAB&usg=AOvVaw01VJGjKqnGNDwt-C9zeG9i

  11. Aguilera Pacheco OR, González Vidal D. Factores pronósticos en la hemorragia cerebral intraparenquimatosa. MEDISAN [internet] 2012 [citado 13/12/2019]; 16 ( 1 ): 21. Disponible en: Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029-30192012000100003

  12. Pérez García AR, García Monter A, Sosa Acosta EF, Padrón Valdés F. Factores pronósticos de mortalidad por hemorragia intracerebral en el periodo agudo. Rev Cub de Medic Milit. [internet] 2015 [citado 13/12/2019]; 44 (3): 277-88. Disponible en: Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-65572015000300002

  13. Brito F, Correiras J, Neves D, Valdir E, Farias L, Ferreira R, et al. Hemorragia Intracerebral Espontánea Estudio retrospectivo de 72 casos operados. Arq Neuropsiquiatr [internet] 2000 [citado 13/12/2019]; 58(2-B): 499-504. Disponible en: Disponible en: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2000000300016

  14. Safatli, D. A., Gunther, A., Schlattmann, P., Schwarz, F., Kalff, R., & Ewald, C. Predictors of 30‐day mortality in patients with spontaneous primary intracerebral hemorrhage. Surg Neurol International [internet]2016 [citado 13/12/2019]; 7 (Suppl. 18), S510-S517. Disponible en: Disponible en: https://dx.doi.org/10.4103/2152-7806.187493

  15. Rahmani F, Rikhtegar R, Ala A, Farkhad-Rasooli A, Ebrahimi-Bakhtavar H. Predicting 30-day mortality in patients with primary intracerebral hemorrhage: Evaluation of the value of intracerebral hemorrhage and modified new intracerebral hemorrhage scores. Iran J Neurol [internet] 2018 [citado 13/12/2019]; 17(1): 47-52. Disponible en: Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121209/

  16. Li Q, Huang YJ, Zhang G, Lv FJ, Wei X, Dong MX, et al. Intraventricular hemorrhage and early hematoma expansion in patients with intracerebral hemorrhage. Scientific Reports. [internet] 2015 [citado 13/12/2019]; 5. Disponible en: Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471897/&sa=U&ved=2ahUKEwjiiNvw_vDoAhVvmeAKHfl8B1QQFjACegQICBAB&usg=AOvVaw2K36N-K0FJW7k2nIC7mn1f

  17. Xia Zhou H, Hao N, Lin Xu N. Related factors of early mortality in young adults with cerebral hemorrhage. Open Med. [internet] 2018 [citado 12/12/2019]; 13: 214-220. Disponible en: Disponible en: https://dx.doi.org/10.1515/med-2018-0033




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Rev Ciencias Médicas. 2020;24