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Coordinación General de Investigación de la Facultad de Salud Pública y Nutrición y la Dirección General de Sistemas e Informática de la Universidad Autónoma de Nuevo León

2022, Number 1

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Rev Salud Publica Nutr 2022; 21 (1)

Effect of omega-3 fatty acids in individuals with obesity: a systematic review

Longoria-Oyervidez ME, Treviño-Casanova KL, Sánchez-Peña MA, Cuellar-Robles S, Nava-González EJ

Language: Spanish
References: 23
Page: 28-35
PDF size: 223.20 Kb.


ABSTRACT

Introduction: Obesity today is a serious public health problem at the global, national and local level, for which the role of omega-3 fatty acids in the regulation of body weight has been studied. Objective: To know the beneficial effect of omega-3 supplementation in obese humans. Material and method: A search was carried out in four online databases where the sample size was 34 to 154 participants, all participants had a BMI› 30 and ‹40 kg / m2 and an average adult age of 18 to 70 years. The duration of the intervention with omega-3 supplementation was 10 to 30 weeks, using a dose of 300 mg to 4 grams. Results: Supplementation with omega-3 fatty acids, for 10 to 30 weeks with a dose of 1 to 3 grams, could help improve body mass index (BMI) and waist-hip index (ICC), as well as than inflammatory modulation in IL8 adipokines and C-reactive protein. Conclusions: The evidence for the efficacy of omega-3 fatty acid supplementation for weight loss is not strong, so it is important to continue researching and reviewing its effects. Study limitations: limited number of studies, in addition to research conducted in animal models.


REFERENCES

  1. Allaire, J., et al. (2017). Supplementation with highdose docosahexaenoic acid increases the Omega- 3 Index more than high-dose eicosapentaenoic acid. Prostaglandins, Leukotrienes and Essential Fatty Acids, 120, 8-14. https://doi.org/10.1016/j.plefa.2017.03.008.

  2. Alex Buoite Stella, et al. (2018). Update on the Impact of Omega 3 Fatty Acids on Inflammation, Insulin Resistance and Sarcopenia: A Review. International Journal of Molecular Sciences, 19(1), 218. https://doi.org/10.3390/ijms19010218.

  3. Castellanos T, L., & Rodriguez D, M. (2015). El efecto de omega 3 en la salud humana y consideraciones en la ingesta. Revista chilena de nutrición, 42(1), 90-95. https://doi.org/10.4067/S0717- 75182015000100012.

  4. DeFina, L. F., et al. (2011). Effects of omega-3 supplementation in combination with diet and exercise on weight loss and body composition. The American Journal of Clinical Nutrition, 93(2), 455-462. https://doi.org/10.3945/ajcn.110.002741.

  5. Delpino, F. M., Figueiredo, L. M., & da Silva, B. G. C. (2021). Effects of omega-3 supplementation on body weight and body fat mass: A systematic review. Clinical Nutrition ESPEN, 44, 122-129. https://doi.org/10.1016/j.clnesp.2021.04.023.

  6. Du, S., Jin, J., Fang, W., & Su, Q. (2015). Does Fish Oil Have an Anti-Obesity Effect in Overweight/Obese Adults? A Meta-Analysis of Randomized Controlled Trials. PLOS ONE, 10(11), e0142652. https://doi.org/10.1371/journal.pone.0142652.

  7. Ellulu, M. S., Patimah, I., Khaza’ai, H., Rahmat, A., & Abed, Y. (2017). Obesity and inflammation: the linking mechanism and the complications. Archives of Medical Science, 4, 851-863. https://doi.org/10.5114/aoms.2016.58928.

  8. Faurot, K. R., et al. (2016). Comparison of a Medication Inventory and a Dietary Supplement Interview in Assessing Dietary Supplement Use in the Hispanic Community Health Study/Study of Latinos. Integrative Medicine Insights, 11, IMI.S25587. https://doi.org/10.4137/IMI.S25587.

  9. González-Acevedo, O., et al (2013). Efecto de la suplementación de omega 3 sobre IMC, ICC y composición corporal en mujeres obesas. Archivos latinoamericanos de nutrición 63(3): 224-231. https://www.alanrevista.org/ediciones/2013/3/art -5/

  10. Higgins JPT, et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ 2011;343 (7829). https://doi.org/10.1136/bmj.d5928.

  11. INEGI-INSP-SSA. (2020). Encuesta Nacional de Salud y Nutrición 2018. https://www.inegi.org.mx/programas/ensanut/20 18/.

  12. Izaola, O. (2015). Inflamación y obesidad (Lipoinflamación). Nutrición Hospitalaria, 6, 2352-2358. https://doi.org/10.3305/nh.2015.31.6.8829.

  13. Keshavarz, S. A., et al. (2018). Omega-3 supplementation effects on body weight and depression among dieter women with comorbidity of depression and obesity compared with the placebo: A randomized clinical trial. Clinical Nutrition ESPEN, 25, 37-43. https://doi.org/10.1016/j.clnesp.2018.03.001.

  14. Kiecolt-Glaser, J. K., et al. (2012). Omega-3 supplementation lowers inflammation in healthy middle-aged and older adults: A randomized controlled trial. Brain, Behavior, and Immunity, 26(6), 988-995. https://doi.org/10.1016/j.bbi.2012.05.011.

  15. Manuel Moreno, G. (2012). Definición y clasificación de la obesidad. Revista Médica Clínica Las Condes, 23(2), 124-128. https://doi.org/10.1016/S0716-8640(12)70288-2.

  16. Mark H. Beers M.D, et al. (2011). (2011) Obesity & the Metabolic Syndrome. The Merck Manual of Diagnosis and Therapy- 19th Ed (pp 108-119).

  17. Mechanick, J. I., et al. (2017). Adiposity-Based Chronic Disease as a new Diagnostic Term: The American Association of Clinical Endocrinologists and American College of Endocrinology Position Statement. Endocrine Practice, 23(3), 372-378. https://doi.org/10.4158/EP161688.PS.

  18. Munro, I. A., & Garg, M. L. (2013). Dietary supplementation with long chain omega-3 polyunsaturated fatty acids and weight loss in obese adults. Obesity Research & Clinical Practice, 7(3), e173-e181. https://doi.org/10.1016/j.orcp.2011.11.001.

  19. Saini, R. K., & Keum, Y. (2018). Omega-3 and omega-6 polyunsaturated fatty acids: Dietary sources, metabolism, and significance — A review. Life Sciences, 203, 255-267. https://doi.org/10.1016/j.lfs.2018.04.049.

  20. Suárez Carmona, W., Sánchez Oliver, A., & González Jurado, J. (2017). Obesidad en México: recomendaciones para una política de Estado. Fisiopatología de la obesidad: Perspectiva actual. Revista chilena de nutrición, 44(3), 226-233. https://doi.org/10.4067/S0717- 75182017000300226.

  21. Spencer, M., et al. (2013). Omega-3 Fatty Acids Reduce Adipose Tissue Macrophages in Human Subjects With Insulin Resistance. Diabetes, 62(5), 1709-1717. https://doi.org/10.2337/db12-1042.

  22. Valenzuela B, A., & Valenzuela B, R. (2014). Acidos grasos omega-3 en la nutrición ¿cómo aportarlos? Revista chilena de nutrición, 41(2), 205-211. https://doi.org/10.4067/S0717- 75182014000200012.

  23. Vors, C., et al. (2017). Inflammatory gene expression in whole blood cells after EPA vs. DHA supplementation: Results from the ComparED study. Atherosclerosis, 257, 116-122. https://doi.org/10.1016/j.atherosclerosis.2017.01.025.




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