medigraphic.com
SPANISH

Acta Médica Grupo Angeles

Órgano Oficial del Hospital Angeles Health System
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
    • Send manuscript
    • Names and affiliations of the Editorial Board
  • Policies
  • About us
    • Data sharing policy
    • Stated aims and scope
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2022, Number 1

<< Back Next >>

Acta Med 2022; 20 (1)

Autoimmune/inflammatory syndrome induced by adjuvants (ASIA): Shoenfeld's syndrome

Domínguez CLG, Arellano AJG
Full text How to cite this article 10.35366/103566

DOI

DOI: 10.35366/103566
URL: https://dx.doi.org/10.35366/103566

Language: Spanish
References: 5
Page: 96-98
PDF size: 177.79 Kb.


Key words:

Adjuvant autoimmune syndrome, breast prosthesis, silicone.

ABSTRACT

Introduction: Adjuvant-induced inflammatory autoimmune syndrome is an entity described in 2011. Its manifestations include myalgias, arthralgias, chronic fatigue and dry mouth, as well as neurological manifestations: cognitive alterations, memory loss and neurological disabilities. Clinical case: 40-year-old female, with breast prostheses for 20 years, who in the last six months has presented: myalgias, fatigue, sensation of joint stiffness and generalized arthralgias, including cervical and lumbar spine, difficulty concentrating at work and sleep disturbances, mood changes with irritability and dyspnea when climbing stairs, increasing fatigue mainly in the pelvic extremities. Relevant laboratory studies showed vitamin D insufficiency, elevated C-reactive protein and increased erythrocyte sedimentation rate (ESR); mammography reported Baker's type II contractures. Breast prosthesis was removed and vitamin D was prescribed, six months postoperatively, the patient was asymptomatic and underwent aerobic exercise five days a week. Conclusion: Silicone implants can produce ASIA syndrome in immunologically susceptible patients.


REFERENCES

  1. Shoenfeld Y, Agmon-Levin N. 'ASIA'- autoimmune/inflammatory syndrome induced by adjuvants. J Autoimmun. 2011; 36 (1): 4-8.

  2. Watad A, Sharif K, Shoenfeld Y. The ASIA syndrome: basic concepts. Mediterr J Rheumatol. 2017; 28 (2): 64-69. doi: 10.31138/mjr.28.2.64.

  3. Watad A, Bragazzi NL, Amital H, Shoenfeld Y. Hyperstimulation of adaptive immunity as the common pathway for silicone breast implants, autoimmunity, and lymphoma of the breast. Isr Med Assoc J. 2019; 21 (8): 517-519.

  4. Fryzek JP, Signorello LB, Hakelius L, Feltelius N, Ringberg A, Blot WJ et al. Self-reported symptoms among women after cosmetic breast implant and breast reduction surgery. Plast Reconstr Surg. 2001; 107 (1): 206-213.

  5. Colaris MJL, van der Hulst RR, Tervaert JWC. Vitamin D deficiency as a risk factor for the development of autoantibodies in patients with ASIA and silicone breast implants: a cohort study and review of the literature. Clin Rheumatol. 2017; 36 (5): 981-993.




Figure 1
Figure 2

2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Acta Med. 2022;20