Vega-Fernández J, Iglesias-Osores S, Tullume-Vergara P

Language: English
References: 5
Page: 1-3
PDF size: 153.68 Kb.

Text Extraction

Mr. director

According the article “Political will and intersectorality to confront COVID-19 in Cuba”, we need to find more recommendations to fight COVID-19. The first sequencing of the SARS-CoV-2 virus began to be published and stored since December 2019. The data generated from genomic studies, such as sequencing, are the basis for studies of molecular epidemiology, population genetics, and studies on diversity genetics.
The use of genomes from sequencing creates new areas to study the details of outbreaks such as molecular epidemiology (MS), is a hybrid of molecular biology within epidemiological studies. Aiming to establish the order of transmission of the pathogen, associate mutations related to its pathogenicity, patterns of transmission of pathogens, reservoirs and source of pathogens.

REFERENCES

1. Leyva Caballero R. Voluntad política e intersectorialidad para el enfrentamiento a la COVID-19 en Cuba. Rev. habanera. cien. méd. [Internet]. 2020 [cited 2020 May 6];19(2):1-5. Available from: http://www.revhabanera.sld.cu/index.php/rhab/article/view/3241/2507

2. Roetzer A, Diel R, Kohl TA, Rückert C, Nübel U, Blom J, et al. Whole Genome Sequencing versus Traditional Genotyping for Investigation of a Mycobacterium tuberculosis Outbreak: A Longitudinal Molecular Epidemiological Study. PLoS Med [Internet]. 2013 [cited 2020 Apr 10];10(2). Available from: https://doi.org/10.1371/journal.pmed.1001387

3. Riapis LA, Filatov NN, Salova NI. Molecular epidemiology of infectious diseases. ZhMikrobiol Epidemiol Immunobiol [Internet]. 2003 [cited 2020 Apr 10];(5):49–54. Available from: https://europepmc.org/article/med/14565124

4. McNaughton AL, Roberts HE, Bonsall D, de Cesare M, Mokaya J, Lumley SF, et al. Illumina and Nanopore methods for whole genome sequencing of hepatitis B virus (HBV). Sci Rep [Internet]. 2019 [cited 2020 Apr 10];9(1):1-14. Available from: https://doi.org/10.1038/s41598-019-43524-9

5. Hadfield J, Megill C, Bell SM, Huddleston J, Potter B, Callender C, et al. Nextstrain: real-time tracking of pathogen evolution. Bioinformatics [Internet]. 2018 [cited 2020 Apr 10];34(23):4121-3. Available from: https://academic.oup.com/bioinformatics/article/34/23/4121/5001388