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2020, Number 3

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Rev Acta Médica 2020; 21 (3)

Skin Sensitivity to Mites in Elderly Patients with Allergic Respiratory Disease

Ginard CA, Ceballos RE, Báez LJM, Figueroa GI, Estruch FIM
Full text How to cite this article

Language: Spanish
References: 23
Page: 2-14
PDF size: 387.96 Kb.


Key words:

atopy, immunosenescence, skin sensitivity.

ABSTRACT

Introduction: Aging causes the immune system to undergo significant changes, a phenomenon called immunosenescence. However, studies in aged adults are few and no strong conclusions exist as to whether atopy, determined by positive skin tests, decreases with age or does not.
Objective: To assess skin sensitivity to mites in aged patients with allergic respiratory disease.
Methods: A case-control study was carried out, between January 2018 and January 2019, with aged patients diagnosed with allergic respiratory disease, all from the protocolized allergy consultations of Hermanos Ameijeiras Clinical-Surgical Hospital. The study population consisted of 60 patients divided into two groups: group A, aged over 60 years old; and group B, aged 18-40 years old. For statistical processing, the variables were compared using the chi-square and Student's t tests.
Results: In both groups, the female sex predominated. The mean age of group A was 67.5±5.6 years. Mild perennial allergic rhinitis (30.0%) and mild persistent asthma (30.0%) were the most frequent diagnoses in group B, while moderate persistent asthma (30.0%) was in group A. In group A, the sensitization profile was described concerning Blomia tropicalis (26.7%), Dermatophagoides Pteronyssinus (23.3%), and Dermatophagoides Siboney (20%); while in group B, the sensitization profile is considered as significantly higher, accounting for 60%, 43.3% and 36.7%, respectively. Regarding histamine values, the characteristics between groups was the same, accounting for 4.5 mm in group A compared to 5.8 mm in group B.
Conclusions: Skin sensitivity to mites in aged patients with allergic respiratory disease was lower than that found in younger patients.


REFERENCES

  1. Ministerio de Salud Pública de Cuba, Dirección de Registros Médicos y Estadísticas de Salud. Anuario Estadístico de Salud, 2017. La Habana: MINSAP: 2017 [acceso 28/02/2019]. Disponible en: https://files.sld.cu/dne/files/2018/04/Anuario-ElectronicoEspa%C3%B1ol-2017-ed-2018.p

  2. Oficina Nacional de Estadística e Información (ONEI). El Envejecimiento de la Población Cubana. Cuba y sus Territorios. Centro de Estudios de Población y Desarrollo. La Habana. 2018 [acceso: 21/03/2019]. Disponible en: https://www.onei.cu/envejecimiento2017.htm

  3. Barrera Salas M, Morales Hernández AE, Hernández Osorio JJ, Hernández Salcedo DR, Valencia López R, Ramírez Crescencio MA. Inmunosenescencia. Med Int Mex. 2017 [acceso: 21/03/2019]; 33(5):696-704. Disponible en: https://www.scielo.org.mx/pdf/mim/v33n5/0186-4866-mim-33-05-696.pdf

  4. Zuo L, Pannell BK, Liu Z. Characterization and redox mechanism of asthma in the elderly. Oncotarget. 2016; 7(18):25010-21.

  5. Salo PM, Arbes SJ Jr, Jaramillo R, Calatroni A, Weir CH, Sever ML, et al. Prevalence of allergic sensitization in the United States: results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006. J Allergy Clin Immunol. 2014 [acceso: 21/03/2019]; 134(2):350-9. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119838

  6. Vega-Robledo GB, Rico-Rosillo MG. Senescencia del sistema inmune y alteraciones relacionadas con el asma. Rev. alerg. Mex 2017 [acceso: 21/03/2019]; 64(2):14-9. Disponible en: https://www.scielo.org.mx/scielo.php?script=sci_serial&pid=24489190&lng=es&nrm=iso

  7. Warm K. The epidemiology of allergic sensitization and the relation to asthmaandrinitis. Department of Public Health and Clinical Medicine, Division of Medicine. 2015.

  8. GEMA. Guía española para el manejo del asma. 2018 [acceso: 21/03/2019]. Disponible en: https://www.semg.es/images/documentos/docs_varios/GEMA_43.pdf

  9. Bousquet J, Hellings PW, Agache I, Bedbrook A, Bachert C, Bergmann KC, et al. ARIA 2016: Care pathways implementing emerging technologies forpredictive medicine in rhinitis and asthma across the life cycle. ClinTransl Allergy.2016 Dec 30 [acceso: 21/03/2019]; 6:47. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203711/

  10. Song WJ, Kim MY, Jo EJ, Kim MH, Kim TH, Kim SH, et al. Rhinitis in a community elderly population: relationships with age, atopy and asthma. Ann Allergy Asthma Immunol. 2013; 111(5):347-51.

  11. Hansen S, Probst-Hensch N, Keidel D, Dratva J, Bettschart R, Pons M, et al. Gender differences in adult-onset asthma: results from the Swiss SAPALDIAcohort study. Eur Resp J. 2015 Oct [acceso: 21/03/2019]; 46(4):1011-20. Disponible en: https://erj.ersjournals.com/content/46/4/1011.long

  12. Pite H, Pereira AM, Morais-Almeida M, Nunes C, Bousquet J, Fonseca JA.P revalence of asthma and its association with rhinitis in the elderly. Resp Med. 2014; 108(8):1117-26.

  13. Liccardi G, Baldi G, Berra A, Ciccarelli A, Cutajar M, D’Amato M, et al. Allergy inurban elderly population living in Campania region (Southern Italy). A multicenter study. Eur Ann Allergy Clin Immunol. 2016;48(4):156-60.

  14. Ventura MT, Scichilone N, Paganelli R, Minciullo PL, Patella V, Bonini M, et al. Allergic diseases in the elderly: biological characteristics and main immunological and non-immunological mechanisms. Clin Mol Allergy. 2017[acceso: 21/03/2019];15:2. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290673/

  15. Ozturk AB and Iliaz S. Challenges in the management of severe allergic asthmain the elderly. J Asthma Allergy. 2016 [acceso: 21/03/2019]; 9:55-63. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803249/

  16. OzyigitPur L, Ozturk AB, Keskin H. Allergic asthma: differences in characteristics between younger and older patients. Rev Fr Allergol. 2015;55(5):379-81.

  17. Inoue H, Niimi A, Takeda T, Matsumoto H, Ito I, Matsuoka H et al. Pathophysiological characteristics of asthma in the elderly: a comprehensive study. Ann Allergy Asthma Immunol. 2014;113(5):527-33. Disponible en: https://pubmed.ncbi.nlm.nih.gov/25216975/

  18. Murray MA, Chotirmall SH. The Impact of Immunosenescence on Pulmonary Disease. Mediators Inflamm. 2015 [acceso: 21/03/2019]; 2015: 692546. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495178/

  19. Ozturk AB, OzyigitPur L, Kostek O, Keskin H. Association between asthma selfmanagement knowledge and asthma control in the elderly. Ann Allergy Asthma Immunol. 2015 [acceso: 21/03/2019]; 114(6):480-4. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/25935432

  20. Li J, Sun B, Huang Y, Lin X, Zhao D, Tan G; China Alliance of Research on Respiratory Allergic Disease (CARRAD). Influence of degree of specific allergic sensitivity on severity of rhinitis and asthma in Chinese allergic patients. Respir Res. 2011 [acceso: 21/03/2019]; 12(1):95. Disponible en: https://respiratory-research.biomedcentral.com/articles/10.1186/1465-9921-12-95

  21. Song WJ, Chang YS. Respiratoryallergies in the elderly: findings from the Korean Longitudinal Study on Health and Aging phase I study (2005-2006). Asia Pac Allergy. 2017 [acceso: 21/03/2019]; 7(4):185-92. Disponible en: https://synapse.koreamed.org/Synapse/Data/PDFData/0253APA/apa-7-185.pdf

  22. Song WJ, Lee SM, Kim MH, Kim SH, Kim KW, Cho SH, Min KU, Chang YS. Histamine and allergen skin reactivity in the elderlypopulation: resultsfrom the Korean Longitudinal StudyonHealth and Aging. Ann Allergy Asthma Immunol. 2011 [acceso: 21/03/2019]; 107:344-52. Disponible en: https://linkinghub.elsevier.com/retrieve/pii/S1081120611005588

  23. Warm K, Hedman L, Lindberg A, Lotvall J, Lundback B, Ronmark E. Allergic sensitization is age-independently associated with rhinitis, but less so with asthma. J Allergy Clin Immunol. 2015 [acceso: 21/03/2019]; 136(6):1559-65.e2. Disponible en: https://www.researchgate.net/publication/280588045_Allergic_sensitization_is_age-dependently_associated_with_rhinitis_but_less_so_with_asthma




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Rev Acta Médica. 2020;21