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2021, Number 1

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Correo Científico Médico 2021; 25 (1)

Oral carcinogenesis

Sánchez SRJ, Sigcho RCR, Bermúdez GAJ, Serrano GNB, Teruel GR
Full text How to cite this article

Language: Spanish
References: 48
Page: 1-23
PDF size: 319.33 Kb.


Key words:

oral cancer, squamous cell carcinoma, carcinogenesis, carcinogens, oncogenes, tumor suppressor genes.

ABSTRACT

Oral cancer is a multifactorial malignant neoplasm where the genetic predisposition to the disease is related to environmental factors to develop cancer with slow evolution and non-specific signs. This bibliographic review was carried out in PMC at the US National Library of Medicine and National Institutes of Health (https://www.ncbi.nlm.nih.gov/pmc), in Cancer Biology of Annual Reviews (https://www.annualreviews.org), in Clinical Key (https://www.clinicalkey.com) and in Infomed (www.sld.cu) using oral cancer as descriptor. Oral carcinogenesis is described as well the factors which bring about changes in the genetic material that cause cancerous transformation by means of the activation of proto-oncogenes to oncogenes and the inactivation of tumor suppressor genes.


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