Ruesga ZE, Estrada GJ

Language: Spanish
References: 20
Page: 143-145
PDF size: 140.32 Kb.

ABSTRACT

In fact, there are a few clinical information about chronobiology and cardiology. At this time we do not have clinical trials in ischemic heart diseases and the circadian ryhtm in our country. The objective of this study was analyze the relationship between this pathology and the chronobiology. The chronotherapy analize the biodisponibility and pharmacokinetics of a product to optimize its effects. Understanding the chronobiology its very important because it means a better quality of treatment in different diseases, it means like the use of hipocholesterolemic products at night or cortisone-like in the morning. In our study showed definitions, circadian variation in physiologic functions, in pathological states like angor pectoris, myocardial infarctions or sudden death.
The knowledge of circadian variation suggest the pharmacological protection during acute periods and it give us end point to clinical investigation to improvement the prevention in this very important disease.

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