García-Correa ML, Chávez-Valencia V, Aguilar-Bixano O, Orizaga-de CC, Rojas-Hernández G, Gómez-de CL

Language: Spanish
References: 20
Page: 7-11
PDF size: 253.73 Kb.

ABSTRACT

Introduction: The renal consequences of kidney donation from a living donor are controversial. The general evidence regarding the risk living kidney donors (LKD) have regarding survival, end-stage kidney disease, cardiovascular and metabolic risks. Objective: To know the frequency of immediate cardiovascular and metabolic complications in related LKD post nephrectomy. Material and methods: Retrospective, cross-sectional, descriptive and analytical study of living kidney donors clinical and demographic variables were recorded, glomerular filtration rate (GFR) was calculated, prevalence of hypertension, diabetes mellitus, obesity and dyslipidemia were assessed. Results: 62 files of related living kidney transplantation between 2006-2019, were reviewed. Donor nephrectomies were left sided in 91.9% of cases. The post-donation evolution time was 53.9 ± 33 months, with an average follow-up to 1 year after renal donation. 54.8% are men, with an average age of 35.6 ± 10 years at the time of donation. 22.5% developed cardiovascular and/or metabolic complications, which were: dyslipidemia, mainly hypertriglyceridemia, followed by hypercholesterolemia. It should be noted that no donor has hypertension or diabetes, although 14% had glucose intolerance. The calculated GFR categorized 88.1% of post-renal donation patients within stage 2 of chronic kidney disease. No patient required post-kidney donation dialysis. Only the pre-donation GFR (p = 0.028) was associated with a GFR less than 60mL/min at 12 months. Conclusions: In short-term the frequency of cardiovascular and metabolic complications LKD such as hypertension, diabetes and proteinuria were zero. Nonpatient developed end-stage kidney disease. So, we may consider kidney donation to be safe in a short term.

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