Salas HLL, Cortés PEC

Language: Spanish
References: 20
Page: 19-23
PDF size: 662.02 Kb.

ABSTRACT

Erythema elevatum diutinum (EED) is a chronic cutaneous disease of unknown origin. Clinically it is characterized by nodules and red-violet plaques mainly affecting acral and extensor surfaces in a symmetrical distribution. The histological hallmark of the disease is a leukocytoclastic vasculitis, with concentric fibrin deposits and microangiopathy at the final stage. We present a 90-year-old female patient who presented purpuric macules and plaques associated with intense erythema, as well as few pruritic and painful papules. At first the patient was treated with topical and systemic steroids as a possible case of contact dermatitis, that worsened her symptoms. The histopathological findings were consistent with eed. Azathioprine 50 mg was added with an adecuate clinical response.

REFERENCES

1. García ME, Martínez SA, Eichelmann K, Gómez M y Ocampo J, Erythema elevatum diutinum: an atypical presentation, The American Journal of the Medical Science 2015; 349:374-5.

2. Momen SE, Jorizzo J y Al-Niaimi F, Erythema elevatum diutinum: a review of presentation and treatment, Journal of the European Academy of Dermatology and Venereology 2014; 28(12):1594-602.

3. Galeone M, Arunachalam M, Bassi A, Scarfi F y Difonzo EM, Clinical picture. Erythema elevatum diutinum, qjm: An International Journal of Medicine 2014; 107:227-8.

4. Vargas F y Arenas R, Eritema elevatum diutinum: artículo de revisión, Dermatología cmq 2008; 6(4):252-61.

5. High WA, Hoang MP, Stevens K y Cockerell CJ, Late stage nodular erythema elevatum diutinum, American Academy of Dermatology 2003; 49(4):764-7.

6. Gibson LE y El-Azhary RA, Erythema elevatum diutinum, Clinics in Dermatology 2000; 18(3):295-9.

7. Schoepe S, Schäcke H, May E y Asadullah K, Glucocorticoid therapy induced skin atrophy, Experimental Dermatology 2006; 15:406-20.

8. Guin JD, Contact sensitivity to topical corticosteroids, Journal of the American Academy of Dermatology 1984; 10(5):773-82.

9. Patnala GP, Sunandini AP, Rayavarapu R y Yandapalli PS, Erythema elevatum diutinum in association with iga monoclonal gammopathy: a rare case report, Indian Dermatology Online Journal 2016; 7(4):300-3.

10. Nakajima H, Ikeda M, Yamamoto Y y Kodama H, Erythema elevatum diutinum complicated by rheumatoid arthritis, The Journal of Dermatology 1999; 26(7): 452-6.

11. Chan Y, Mok CC y Tang WY, Erythema elevatum diutinum in systemic lupus erythematosus, Rheumatology International 2011; 31(2):259-62.

12. Tasanen K, Raudasoja R, Kallioinen M y Ranki A, Erythema elevatum diutinum in association with coeliac disease, The British Journal of Dermatology 1997; 136(4):624-7.

13. Stringa O, Pascutto C, Caiafa D y Civitillo C, Eritema elevatum diutinum e infección por vih, Dermatología Argentina 2007; 13(4):257-61.

14. Benedetto J, Pinto MP, Saavedra J, Cabrera R y Castro A, Eritema elevatum diutinum. Reporte de dos casos y revisión de la literatura, Revista Chilena de Dermatología 2010; 26(2):164-8.

15. Al Abadie M, Oumeish F, Al-Rubaye M y Tariq A, Update and review of the treatment of erythema elevatum diutinum, Biomedical Journal of Scientific & Technical Research 2019; 21(5):16176-8.

16. Rodríguez E, Galache C, Junquera ML, Nosti D, Martínez A y Suárez R, Eritema elevatum et diutinum con afectación palmar y asociación con p-anca, Actas Dermosifiliográficas 2002; 93(8):501-6.

17. Sardiña LA, Jour G, Piliang M y Bergfeld WF, Erythema elevatum diutinum a rare and poorly understood cutaneous vasculitis: a single institution experience, Journal of Cutaneous Pathology 2019; 46(2):97-101.

18. Wollina U, Krönert C, Koch A, Schönlebe J, Vojvodic A y Lotti T, Erythema elevatum ciutinum: two case reports, two different clinical presentations, and a short literature review, Open Access Macedonian Journal of Medical Sciences 2019; 7(18):3039-42.

19. Bevans S, Keeley J y Sami N, Erythema elevatum diutinum treated with mycophenolate mofetil, Journal of Clinical Rheumatology 2019; 25(6):e93-4.

20. Meza CM, Dehesa E, Ruelas AG y Peña E, Vasculitis leucocitoclástica: un reto diagnóstico para el médico internista, Medicina Interna de México 2015; 31(1):113-8.