2021, Number 1
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ABSTRACTIntroduction: A probable association has been described between the presence of osteopenia/osteoporosis and the increased risk of ischemic heart disease.
Objective: To determine the possible association between the presence of acute coronary syndrome and decreased bone mineral density, as well as the relationship of both conditions with some cardiovascular risk factors and variables of the reproductive sphere in women during the climacteric stage.
Method: A descriptive and cross-sectional study was carried out with 72 women (34 with acute coronary syndrome and 38 without acute coronary syndrome), who were selected from databases of the Institute of Cardiology and Cardiovascular Surgery. Bone mineral density was determined by dual lumbar spine X-ray absorptiometry. The chi-square and Mann Whitney U tests allowed to evaluate the possible relationship between variables.
Results: 55.9% of the patients with acute coronary syndrome and 60.5% of the women without acute coronary syndrome had decreased bone mineral density. Among women with decreased bone mineral density (n=42), 81% had abdominal obesity, 78.6% had dyslipoproteinemia, 83.3% had arterial hypertension, and 76.2% had a family history of ischemic heart disease.
Conclusions: In the women in the climacteric stage studied, no association was shown between the presence of acute coronary syndrome and decreased bone mineral density. There was no relationship either between the presence of acute coronary syndrome and decreased bone mineral density with cardiovascular risk factors, or with variables in the reproductive sphere.
Hadad AN, Pérez LM. Primer consenso nacional de dislipoproteinemias: Guía nacional para la prevención, detección, diagnóstico y tratamiento de las dislipoproteinemias. 2012 [Consultado 02 marzo 2021] Disponible en: Disponible en: http://www.hospitalameijeiras.sld.cu/hha/sites/all/informacion/mpm/documentos/PROTOCOLOS/MEDICINA%20INTERNA/DISLIPOPROTEINEMIAS%20FAMILIARES.pdf
Aspera-Werz RH, Chen T, Ehnert S, Zhu S, Fröhlich T, Nussler AK. Cigarette smoke induces the risk of metabolic bone diseases: Transforming growth factor beta signaling impairment via dysfunctional primary cilia affects migration, proliferation, and differentiation of human mesenchymal stem cells. Int J Mol Sci. 2019;20(12):1-19.