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2020, Number 3

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Rev Cubana Estomatol 2020; 57 (3)

Antibacterial effect of endodontic sealers in root canals

Concha CE, Chino B, Acevedo OAC, Argueta FL

Language: Spanish
References: 33
Page: 1-14
PDF size: 338.79 Kb.


ABSTRACT

Introduction: Endodontic sealers play a crucial role in sealing, for they not only act at the moment of their application, but continue to do so later, protecting the apical periodontium against microbial organisms. One of the properties desired in endodontic sealers is precisely their antimicrobial action against bacteria remaining after irrigation and instrumentation.
Objective: Carry out a systematic review about the antibacterial effect of the endodontic sealers most commonly used in dental practice against Enterococcus faecalis (E. faecalis).
Methods: The systematic review was based on PRISMA guidelines. The search was conducted in the databases PubMed and Science Direct. Papers were reviewed which dealt with in vitro antimicrobial studies about endodontic sealers, excluding secondary sources such as literature reviews and papers about cements used for other purposes.
Discussion: Cements based on calcium hydroxide, resin or bioceramic are biocompatible and display some percentage of antimicrobial activity. However, variability was observed in the results obtained by the studies in the review, due to the use of different conditions for antibacterial evaluation, except for silicone-based endodontic sealers, which consistently displayed no antibacterial activity against E. faecalis.
Conclusion: According to the bibliography reviewed, the sealers AH Plus, AH 26, TotalFill, BC Sealer and MTA Fillapex had an antimicrobial effect. However, some of them displayed scant activity against E. faecalis.


REFERENCES

  1. Prestegaard H, Portenier I, Orstavik D, Kayaoglu G, Haapasalo M, Endal U. Antibacterial activity of various root canal sealers and root-end filling materials in dentin blocks infected ex vivo with Enterococcus faecalis. Acta Odontol Scand 2014 [acceso: 07/01/2019];72(8). Disponible en: https://www.tandfonline.com/doi/abs/10.3109/00016357.2014.931462

  2. Vilela Teixeira AB, de Carvalho Honorato Silva C, Alves OL, Candido Dos Reis A. Endodontic Sealers Modified with Silver Vanadate: Antibacterial, Compositional, and Setting Time Evaluation. Biomed Res Int 2019[acceso: 07/01/2019];2019(1). Disponible en: https://www.hindawi.com/journals/bmri/2019/4676354/abs/

  3. Gong SQ, Huang ZB, Shi W, Ma B, Tay FR, Zhou B. In vitro evaluation of antibacterial effect of AH Plus incorporated with quaternary ammonium epoxy silicate against Enterococcus faecalis. J Endod 2014[acceso: 07/01/2019];40(10). Disponible en: https://www.sciencedirect.com/science/article/pii/S0099239914003057

  4. Fuss Z, Weiss EI, Shalhav M. Antibacterial activity of calcium hydroxide-containing endodontic sealers on Enterococcus faecalis in vitro. Int Endod J 1997[acceso: 09/01/2019];30(6). Disponible en: https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1365-2591.1997.00103.x

  5. Moher D, Liberati A, Tetzlaff J, Altman DG, Group P. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol 2009[acceso: 09/01/2019];62(10). Disponible en: https://annals.org/aim/fullarticle/744664/preferred-reporting-items-systematic-reviews-meta-analyses-prisma-statement

  6. Camilleri J. Evaluation of selected properties of mineral trioxide aggregate sealer cement. J Endod 2009[acceso: 09/01/2019];35(10). Disponible en: https://www.sciencedirect.com/science/article/pii/S009923990900613X

  7. Saunders WP, Saunders EM. Coronal leakage as a cause of failure in root-canal therapy: a review. Endod Dent Traumatol 1994[acceso: 09/01/2019];10(3). Disponible en: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-9657.1994.tb00533.x

  8. Ørstavik D. Materials used for root canal obturation: technical, biological and clinical testing. Endodontic Topics 2005[acceso: 14/01/2019];12(1). Disponible en: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1601-1546.2005.00197.x

  9. Islam I, Chng HK, Yap AU. Comparison of the physical and mechanical properties of MTA and portland cement. J Endod 2006[acceso: 14/01/2019];32(3). Disponible en: https://www.sciencedirect.com/science/article/pii/S009923990500083X

  10. Thosar NR, Chandak M, Bhat M, Basak S. Evaluation of Antimicrobial Activity of Two Endodontic Sealers: Zinc Oxide with Thyme Oil and Zinc Oxide Eugenol against Root Canal Microorganisms- An in vitro Study. Int J Clin Pediatr Dent 2018[acceso: 14/01/2019];11(2). Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034054/pdf/ijcpd-11-079.pdf

  11. Liu C, Shao H, Chen F, Zheng H. Rheological properties of concentrated aqueous injectable calcium phosphate cement slurry. Biomaterials 2006[acceso: 14/01/2019];27(29). Disponible en: https://www.sciencedirect.com/science/article/pii/S0142961206004947

  12. Coomaraswamy KS, Lumley PJ, Hofmann MP. Effect of bismuth oxide radioopacifier content on the material properties of an endodontic Portland cement-based (MTA-like) system. J Endod 2007[acceso: 14/01/2019];33(3). Disponible en: https://www.sciencedirect.com/science/article/pii/S0099239906010661

  13. Lin Z, Ling J, Fang J, Liu F, He J. Physicochemical properties, sealing ability, bond strength and cytotoxicity of a new dimethacrylate-based root canal sealer. J Formos Med Assoc 2010[acceso: 14/01/2019];109(11). Disponible en: https://core.ac.uk/download/pdf/82357146.pdf

  14. Pameijer CH, Zmener O. Resin materials for root canal obturation. Dent Clin North Am 2010[acceso: 14/01/2019];54(2). Disponible en: https://www.dental.theclinics.com/article/S0011-8532(09)00112-8/pdf

  15. Paranjpe A, Zhang H, Johnson JD. Effects of mineral trioxide aggregate on human dental pulp cells after pulp-capping procedures. J Endod 2010[acceso: 14/01/2019];36(6). Disponible en: https://www.sciencedirect.com/science/article/pii/S0099239910001391

  16. Mozayeni MA, Zadeh YM, Paymanpour P, Ashraf H, Mozayani M. Evaluation of push-out bond strength of AH26 sealer using MTAD and combination of NaOCl and EDTA as final irrigation. Dent Res J (Isfahan) 2013[acceso: 14/01/2019];10(3). Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760360/?report=reader

  17. Ahuja L, Jasuja P, Verma KG, Juneja S, Mathur A, Walia R, et al. A Comparative Evaluation of Sealing Ability of New MTA Based Sealers with Conventional Resin Based Sealer: An In-vitro Study. J Clin Diagn Res 2016[acceso: 14/01/2019];10(7). Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/27630959

  18. Silva EJ, Accorsi-Mendonca T, Pedrosa AC, Granjeiro JM, Zaia AA. Long-Term Cytotoxicity, pH and Dissolution Rate of AH Plus and MTA Fillapex. Braz Dent J 2016[acceso: 14/01/2019];27(4). Disponible en: http://www.scielo.br/scielo.php?pid=S0103-64402016000400419&script=sci_arttext

  19. Thu M, Kim J-W, Park S-H, Cho K-M. Physical properties of a new resin-based root canal sealer in comparison with AH Plus Jet. J Dent Rehabil Appl Sci 2017[acceso: 14/01/2019];33(2). Disponible en: http:///journal/view.html?doi=10.14368/jdras.2017.33.2.80

  20. Alsubait S, Albader S, Alajlan N, Alkhunaini N, Niazy A, Almahdy A. Comparison of the antibacterial activity of calcium silicate- and epoxy resin-based endodontic sealers against Enterococcus faecalis biofilms: a confocal laser-scanning microscopy analysis. Odontology 2019[acceso: 14/01/2019];107(4). Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/30927150

  21. Huang Y, Li X, Mandal P, Wu Y, Liu L, Gui H, et al. The in vitro antimicrobial activities of four endodontic sealers. BMC Oral Health 2019[acceso: 14/01/2019];19(1). Disponible en: https://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-019-0817-2

  22. Zordan-Bronzel CL, Tanomaru-Filho M, Rodrigues EM, Chavez-Andrade GM, Faria G, Guerreiro-Tanomaru JM. Cytocompatibility, bioactive potential and antimicrobial activity of an experimental calcium silicate-based endodontic sealer. Int Endod J 2019[acceso: 14/01/2019];52(7). Disponible en: https://onlinelibrary.wiley.com/doi/abs/10.1111/iej.13086

  23. Kapralos V, Koutroulis A, Orstavik D, Sunde PT, Rukke HV. Antibacterial Activity of Endodontic Sealers against Planktonic Bacteria and Bacteria in Biofilms. J Endod 2018[acceso: 14/01/2019];44(1). Disponible en: https://www.sciencedirect.com/science/article/pii/S0099239917309755

  24. Shakya VK, Gupta P, Tikku AP, Pathak AK, Chandra A, Yadav RK, et al. An Invitro Evaluation of Antimicrobial Efficacy and Flow Characteristics for AH Plus, MTA Fillapex, CRCS and Gutta Flow 2 Root Canal Sealer. J Clin Diagn Res 2016[acceso: 14/01/2019];10(8). Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/27656550

  25. Candeiro GTM, Moura-Netto C, D'Almeida-Couto RS, Azambuja-Junior N, Marques MM, Cai S, et al. Cytotoxicity, genotoxicity and antibacterial effectiveness of a bioceramic endodontic sealer. Int Endod J 2016[acceso: 14/01/2019];49(9). Disponible en: https://onlinelibrary.wiley.com/doi/abs/10.1111/iej.12523

  26. Kangarlou A, Neshandar R, Matini N, Dianat O. Antibacterial efficacy of AH Plus and AH26 sealers mixed with amoxicillin, triple antibiotic paste and nanosilver. J Dent Res Dent Clin Dent Prospects 2016[acceso: 2019 Ene 14];10(4): [aprox. 6 p.]. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/28096947

  27. Wainstein M, Morgental RD, Waltrick SB, Oliveira SD, Vier-Pelisser FV, Figueiredo JA, et al. In vitro antibacterial activity of a silicone-based endodontic sealer and two conventional sealers. Braz Oral Res 2016[acceso: 14/01/2019];30(4). Disponible en: http://www.scielo.br/scielo.php?pid=S1806-83242016000100216&script=sci_arttext

  28. Jafari F, Samadi Kafil H, Jafari S, Aghazadeh M, Momeni T. Antibacterial Activity of MTA Fillapex and AH 26 Root Canal Sealers at Different Time Intervals. Iran Endod J 2016[acceso: 14/01/2019];11(3). Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/27471530

  29. Dissanayaka WL, Zhu L, Hargreaves KM, Jin L, Zhang C. In vitro analysis of scaffold-free prevascularized microtissue spheroids containing human dental pulp cells and endothelial cells. J Endod 2015[acceso: 14/01/2019];41(5). Disponible en: https://www.sciencedirect.com/science/article/pii/S0099239914012278

  30. Shin JH, Lee DY, Lee SH. Comparison of antimicrobial activity of traditional and new developed root sealers against pathogens related root canal. J Dent Sci 2018[acceso: 14/01/2019];13(1). Disponible en: https://www.sciencedirect.com/science/article/pii/S1991790218300333

  31. Gandhi B, Halebathi-Gowdra R. Comparative evaluation of the apical sealing ability of a ceramic based sealer and MTA as root-end filling materials - An in-vitro study. J Clin Exp Dent 2017[acceso: 14/01/2019];9(7). Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/28828158

  32. Ruiz-Linares M, Baca P, Arias-Moliz MT, Ternero FJ, Rodriguez J, Ferrer-Luque CM. Antibacterial and antibiofilm activity over time of GuttaFlow Bioseal and AH Plus. Dent Mater J 2019[acceso: 14/01/2019];38(5). Disponible en: https://www.jstage.jst.go.jp/article/dmj/38/5/38_2018-090/_article/-char/ja/

  33. Wang QQ, Zhang CF, Chu CH, Zhu XF. Prevalence of Enterococcus faecalis in saliva and filled root canals of teeth associated with apical periodontitis. Int J Oral Sci 2012[acceso: 14/01/2019];4(1). Disponible en: https://www.nature.com/articles/ijos201217




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