medigraphic.com
SPANISH

Revista Mexicana de Pediatría

ISSN 0035-0052 (Print)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
    • Send manuscript
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2021, Number 6

<< Back Next >>

Rev Mex Pediatr 2021; 88 (6)

Guillain-Barré syndrome associated with SARS-CoV-2 infection

García-Melo LM, García-Reynoso VM, Espíndola-Gleason E, Solana-Rojas Á
Full text How to cite this article 10.35366/105424

DOI

DOI: 10.35366/105424
URL: https://dx.doi.org/10.35366/105424

Language: Spanish
References: 11
Page: 228-232
PDF size: 236.54 Kb.


Key words:

Guillain-Barré syndrome, SARS-CoV-2, COVID-19, neuropathy, children.

ABSTRACT

Introduction: Guillain-Barré syndrome (GBS) is an acute inflammatory demyelinating polyradiculoneuropathy characterized by flaccid, areflexic, ascending and symmetrical paralysis, which may have an infectious origin. It has recently been associated with COVID-19. Case presentation: Two pediatric patients with GBS and in whom COVID-19 was diagnosed by PCR are described. In both patients, the diagnosis of GBS was confirmed by neuroconduction studies. Both received treatment with immunoglobulin and had complete resolution of the neurological symptoms. Conclusions: Given that GBS can occur in pediatric patients with COVID-19, both conditions should be suspected in patients with clinical data similar to the cases reported here.


REFERENCES

  1. Aragón-Nogales R, Vargas-Almanza I, Miranda-Novales MG. COVID-19 por SARS-CoV-2: la nueva emergencia de salud. Rev Mex Pediatr. 2019; 86(6): 213-218.

  2. Zhao H, Shen D, Zhou H, Liu J, Chen S. Guillain-Barré syndrome associated with SARS-CoV-2 infection: causality or coincidence? Lancet Neurol. 2020; 19(5): 383-384.

  3. Abu-Rumeileh S, Abdelhak A, Foschi M et al. Guillain-Barré syndrome spectrum associated with COVID-19: an up-to-date systematic review of 73 cases. J Neurol. 2021; 268(4): 1133-1170. doi: 10.1007/s00415-020-10124-x.

  4. Esteban MA, Mata MM, Sánchez CP et al. Síndrome de Guillain-Barré asociado a infección por COVID-19. Med Intensiva. 2020; 44(8): 513-514.

  5. Mao L, Wang M, Chen SH et al. Neurological manifestations of hospitalized patients with COVID-19 in Wuhan, China. JAMA Neurol. 2020; 77(6): 683-690.

  6. Kam KQ, Yung CF, Cui L et al. A well infant with coronavirus disease 2019 with high viral load. Clin Infect Dis. 2020; 71(15): 847-849.

  7. Huang C, Wang Y, Li X et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020; 395(10223): 497-506.

  8. Jacobs BC, Rothbarth PH, van der Meché FG et al. The spectrum of antecedent infections in Guillain-Barré syndrome: a case-control study. Neurology. 1998; 51(4): 1110-1105.

  9. De Wit E, van Doremalen N, Falzarano D, Munster VJ. SARS and MERS: recent insights into emerging coronaviruses. Nat Rev Microbiol. 2016; 14: 523-534.

  10. Sharma K, Tengsupakul S, Sanchez O, Phaltas R, Maertens P. Guillain-Barré syndrome with unilateral peripheral facial and bulbar palsy in a child: a case report. SAGE Open Med Case Rep. 2019; 7: 2050313X19838750.

  11. Paybast S, Gorji R, Mavandadi S. Guillain-Barré syndrome as a neurological complication of novel COVID-19 infection: a case report and review of the literature. Neurologist. 2020; 25(4): 101-103.




Figure 1
Table 1
Table 2

2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Rev Mex Pediatr. 2021;88