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2021, Number 1

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Rev Cub Med Mil 2021; 50 (1)

COVID-19 positive asymptomatic patients

Ruiz NJB, Ruiz NK
Full text How to cite this article

Language: Spanish
References: 30
Page:
PDF size: 193.83 Kb.


Key words:

coronavirus, SARS-CoV-2, pandemic, COVID-19, asymptomatic patients.

ABSTRACT

Introduction: COVID-19 is an emerging disease of pandemic category. The clinical forms are variable and the asymptomatic form has high frequency.
Objective: To describe the clinical and epidemiological characteristics of COVID-19 positive and asymptomatic patients.
Methods: A descriptive study was carried out, including all asymptomatic patients on admission, whit a confirmed diagnosis, by the real-time reverse transcriptase-polymerase chain reaction test for SARS-CoV-2 infection at Military Hospital “Dr. Fermín Valdés Domínguez” from March to July 2020. The variables age, sex, clinical expressiveness, clinical and epidemiological history were studied. Frequencies and percentage were used.
Results: The 41,8 percent of the patients remained asymptomatic, the age group between 20 and 39 years (33,3 %) and female sex predominated (55,6 %). The most frequent source of infection was contact with confirmed case (88,9 %) and the most frequent municipalities were Holguín, Gibara and Banes. Older adults and hypertension were most frequent clinical risk factors (20,0 and 57,8 % respectively) and 57,8 % of the patients had no comorbidities.
Conclusions: Young adults predominated, female sex, from Holguín, Gibara and Banes municipalities with a history of being a contact confirmed case. Elderly condition and hypertension were the most frequent risk factors and most of the cases did not have comorbidities.


REFERENCES

  1. Wang Y, Wang Y, Chen Y, Qin Q. Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID-19) implicate special control measures. J Med Virol. 2020 [acceso: 05/07/2020];92(6):568-576. Disponible en: http://www.doi.org/10.1002/jmv.25748

  2. Yinghao C, Xiaoling L, Lijuan X, Kailin C. Imaging and clinical features of patients with 2019 novel coronavirus SARS -CoV -2: A systematic review and meta-analysis. J Med Virol. 2020 [acceso: 15/07/2020];92(10):1449-1459. Disponible en: http://www.doi.org/10.1002/jmv.25822

  3. WHO Coronavirus Disease (COVID-19) Dashboard. WHO. 2020 [acceso: 15/072020]. Disponible en: https://covid19.who.int/?gclid=EAIaIQobChMIrLW_poyo7QIVxNrICh2Z6Q5OEAAYASAAEgICfvD_BwE

  4. Chaolin H, Yeming W, Xingwang L, Lili R, Jianping Z, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020 [acceso: 5/07/2020]; 395(10223):497-506. Disponible en: https://doi.org/10.1016/S0140-6736(20)30183-5

  5. Hernández Rodríguez J. Aspectos clínicos relacionados con el Síndrome Respiratorio Agudo Severo (SARS-CoV-2). Rev haban cienc méd. 2020 [acceso: 15/07/2020]; 19(Supl.): e3279. Disponible en: https://www.revhabanera.sld.cu/index.php/rhab/article/view/3279

  6. Pérez Abreu M, Gómez Tejeda J, Dieguez Guach R. Características clínico-epidemiológicas de la COVID-19. Rev haban cienc méd. 2020 [acceso: 15/07/2020]; 19(2):e_3254. Disponible en: https://www.revhabanera.sld.cu/index.php/rhab/article/view/3254/2505

  7. Chen Y, Liu Q, Guo D. Emerging coronaviruses: genome structure, replication, and pathogenesis. J Med Virol. 2020[acceso: 10/07/2020]; 92(4):418-423. Disponible en: https://pubmed.ncbi.nlm.nih.gov/31967327/

  8. Pérez Fernández A, Suárez Hernández R, Rodríguez González E, Sarda Rojas J. Predictores de la aparición de síntomas en pacientes cardiópatas con la COVID- 19 asintomáticos al ingreso. Rev Cuban Cardiol. 2020 [acceso: 10/07/2020];26(2): e999. Disponible en: https://www.revcardiologia.sld.cu/index.php/revcardiologia/article/view/999

  9. Cobas Planchez L, Mezquia de-Pedro N, Armenteros Terán S. Características clínicas de pacientes con sospecha de COVID-19 ingresados en el hospital "Frank País García", La Habana. Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta. 2020 [acceso: 13/07/2020];45(4). [aprox. 6 p.] Disponible en: https://www.revzoilomarinello.sld.cu/index.php/zmv/article/view/2339

  10. World Medical Association. World Medical declaration of Helsinki: ethical principles for medical research involving human subjects. J Am Med Assoc. 2013. [acceso: 20/07/2020]; 310(29): 2191-2194. Disponible en: http://pubmed.ncbi.nlm.nih.gov/24141714/

  11. Nishiura H, Kobayashi T, Miyama T, Suzuki A, Jung SM, Hayashi K, et al. Estimation of the asymptomatic ratio of novel coronavirus infections (COVID-19). Int J Infect Dis. 2020 [acceso: 1/07/2020];94:154-155. Disponible en: https://www.ncbi.nlm.gov/pmc/articles/PMC7270890

  12. Tan J, Liu Sh, Zhuang L, Chen L Dong, Mengzhen, Zhang Jie, et al. Transmission and clinical characteristics of asymptomatic patients with SARS-CoV-2 infection. Future virol. 2020 [acceso: 5/07/2020]; 15(6):373-380. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291769

  13. Gao Z, Yinghui X, Chao S, Xu W, Ye G, Shi Q, et al. A systematic review of asymptomatic infections with COVID-19. Journal of Microbiology, Immunology and Infection. 2020 [acceso: 5/07/2020]; En prensa. Disponible en: https://doi.org/10.1016/j.jmii.2020.05.001

  14. Wu Z, McGoogan J. Asymptomatic a pre-Symptomatic COVID-19 in China. Infect Dis Poverty. 2020 [acceso: 10/07/2020]; 9 (72): [aprox. 2 p.] Disponible en: http://idpjournal.biomedcentral.com/articles/10.1186/s40249-020-00679-2

  15. Cai J, Lin D, Yang Z, Xu L Qu Z, et al. A Cases Series of children with 2019 novel coronavirus infection: clinical and epidemiological features. Rev Clin Infect Dis. 2020 [acceso: 19/07/2020]; 71(16):1547-1551. Disponible en: https://academic.oup.com/cid/advence-article/10.1093/cid/ciaa198/

  16. Mizumoto K, Kogaya K, Zarebski A, Chowell G. Estimating the asymptomatic proportion of coronavirus diseases 2019 (COVID-19) cases on board the Diamond Princess cruise ship, Yokohama, Japan, 2020. Euro surveill. 2020 [acceso: 10/07/2020]; 25 (10): [aprox. 5 p.]. Disponible en: https://www.doi.org/10.2807/1560-7917

  17. Albalate M, Arribas P, Torres E, Cintra M, Alcázar R, Puerta M, et al. Alta prevalencia de la COVID-19 asintomáticos en hemodiálisis. Aprendiendo día a día el primer mes de la pandemia de COVID-19. Nefrología. 2020 [acceso: 10/07/2020]; 40(3):279-86. Disponible en: https://www.sciencedirect.com/science/article/pii/s2013251420300754

  18. Pollan M, Pérez Gómez B, Pastor Barriuso R, Oteo J, Hernán M, Pérez Olmeda M, et al. Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemilogical study. The Lancet. 2020 [acceso: 10/07/2020];396(10250): 535-44. Disponible en: https://www.thelancet.com/journal/lancet/onlinefirst

  19. Montano Luna J, Tamarit Díaz T, Rodríguez Hernández O, Zelada Pérez M, Rodríguez Zelada C. La pesquisa activa. Primer eslabón del enfrentamiento a la COVID-19 en el Policlínico Docente "Antonio Maceo". Rev haban cienc méd. 2020 [acceso: 15/07/2020]; 19(Supl.):e_3413. Disponible en: https://www.revhabanera.sld.cu/index.php/rhab/article/view/3413

  20. Ferrer Castro J, Sánchez Hernández E, Poulout Mendoza A, del Río Caballero G, Figueredo Sánchez D. Caracterización clínica y epidemiológica de pacientes confirmados con la COVID-19 en la provincia de Santiago de Cuba. MEDISAN. 2020 [acceso: 16/07/2020];24(3):[aprox. 12 p]: Disponible en: https://medisan.sld.cu/index.php/san/article/view/3145

  21. Aguilar Hernández I, Wong Corrales L, Perera Milian L, Hernández Pérez R. Caracterización de los casos confirmados de la COVID-19 en Mayabeque. Medimay. 2020 [acceso: 5/07/2020];27(2):230-236. Disponible en: https://medimay.sld.cu/index.php/rcmh/article/view/1660

  22. Urquiza Yero Y, Pérez Ojeda M, Cortés González A, Escalona Pérez I, Cabrales León M. Características clínico epidemiológicas de los pacientes de Las Tunas positivos al RT-PCR para la COVID-19. Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta. 2020 [acceso: 10/07/2020]; 45(4): [aprox. 9 p.]. Disponible en: https://revzoilomarinello.sld.cu/index.php/zmv/article/view/2361

  23. Medina Fuentes G, Carbajales León E, Figueredo González Y, Carbajales León A, Silva Corona I. Características clínico epidemiológicas de pacientes positivos a la COVID-19 pertenecientes al policlínico "Joaquín de Agüero y Agüero", Camagüey. Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta. 2020 [acceso: 1/07/2020]; 45(4): [aprox. 5 p.]. Disponible en: http://revzoilomarinello.sld.cu/index.php/zmv/article/view/2352

  24. Hu Z, Song C, Xu C, Jin G, Chen Y, Xu X, et al. Clinical characteristics of 24 asymptomatic infections with COVID-19 screened among close contacts in Nanjing, China. Sci China Life Sci. 2020 [acceso: 20/07/2020]; 63(5):706-711. Disponible en: https://doi.org/10.1007/s11427-020-1661-4

  25. Fox S, Pasco R, Tec M, Du Z, Lachmann M, Meyers L. The impact of asymptomatic COVID-19 infections on future pandemic waves. MedRxiv. 2020 [acceso: 15/07/2020]. [aprox. 6 p.]. Disponible en: https://www.medrxiv.org/content/10.1101/2020.06.22.20137489v1

  26. Cummings M, Baldwin M, Abrams D, Jacobson S, Meyer B, Balough E, et al. Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study. Lancet. 2020 [acceso: 10/07/2020]; 395(10239):1763-70: Disponible en: https://www.doi.org/10.1016/S0140-6736(20)31189-2

  27. Escobar G, Matta J, Taype-Huamaní W, Ayala R, Amado J. Características Clínico epidemiológicas de pacientes fallecidos por COVID-19 en un Hospital Nacional de Lima, Perú. Rev. Fac. Med. Hum. 2020 [acceso: 4/07/2020]; 20(2):180-185. Disponible en: https://www.doi.org/10.25176/RFMH.v20i2.2940

  28. Acosta G, Escobar G, Bernaola G, Alfaro J, Taype W, Marcos C, et al. Caracterización de pacientes con COVID-19 grave atendidos en un hospital de referencia nacional del Perú. Rev Peru Med Exp Salud Publica. 2020 [acceso: 25/07/2020]; 37(2):253-258. Disponible en: http://www.scielo.org.pe/scielo.php?pid=S1726-46342020000200253&script=sci_arttext

  29. Wenham C, Smith J, Morgan R. COVID-19: the gendered impacts of the outbreak. The lancet. 2020 [acceso: 7/07/2020]; 395(10227):846-848. Disponible en: https://www.doi.org/10.1016/s0140-6736(20)30526-2

  30. Guzmán O, Lucchesi E, Trelles M, Pinedo R, Camere M, Daly A, et al. Características clínicas y epidemiológicas de 25 casos de COVID-19 atendidos en la Clínica Delgado de Lima. Rev Soc Peru Med Interna. 2020 [acceso: 29/06/2020]; 33(1): 15-24. Disponible en: https://www.revistamedicinainterna.net/index.php/spmi/article/view/506




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Rev Cub Med Mil . 2021;50