Yalaupari-Mejía JP, Arellano-Galindo J, Mancilla-Ramírez J, Rojas-Escobar V, Reyes-Gómez U, Reyes-Hernández KL

Language: Spanish
References: 15
Page: 15-18
PDF size: 171.16 Kb.

ABSTRACT

Tuberculosis has a high prevalence around the world, in México tuberculosis occurs in 6.63% of people under 20 years of age. BCG vaccine prevents against meningeal and ganglion tuberculosis, although its extended use, local and widespread adverse effects have been reported in low frequency, and lymphangitis is the most common. Our objective was to describe the clinical evolution of five newborns who accidentally received overdose of BCG vaccine. Description of cases: Five newborns were vaccinated accidentally with twice the doses of BCG vaccine. They were evaluated at 11 and 41 days and then, at 3, 6, 9 and 12 months after vaccination. Clear and accurate information was provided to parents. After 52 weeks, no patient had adverse effect attributable to vaccination. The reactogenicity of BCG vaccine remains low and it depends of severe factors such as the patient immune status, dose, route of administration and the strain of vaccine. Good communication to parents of patients is indispensable.

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