2022, Number 3
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Med Int Mex 2022; 38 (3)
Madelung’s disease
Agudelo-Sanabria MB, Rozo-Ortiz EJ, Vargas-Rodríguez LJ
Language: Spanish
References: 10
Page: 718-721
PDF size: 174.24 Kb.
ABSTRACT
Background: Madelung’s disease is also known as multiple symmetric lipomatosis,
benign symmetric lipomatosis, and Launois-Bensaude syndrome. It is a rare disorder
characterized by a progressive, excessive and symmetrical accumulation of adipose
tissue in the subcutaneous layer.
Clinical case: A 58-year-old male with an 8-month evolution clinical picture
consisting of the appearance of masses in different parts of the body and a considerable
increase in the size of the gluteal region. He had a history of chronic
alcoholism. On physical examination, accumulations of a smooth and painless
consistency were observed on palpation on the external face of the arms and
abdomen, and an increase in the size of the buttocks with fatty characteristics
with a level of pain on palpation was also evident. The biopsy confirmed the
presence of adipose tissue in the lesions and ruled out tumor infiltration, thus
confirming Madelung’s syndrome.
Conclusions: Madelung’s syndrome is a low prevalence disease, which is associated
with modifiable and non-modifiable risk factors, within the latter the patient in the case
presented was exposed to alcoholism. This is a patient with phenotypic characteristics
of Madelung syndrome, from whom other probable differential diagnoses were downloaded
and diagnosis was confirmed by histopathological study.
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