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ISSN 1561-3186 (Electronic)

2021, Number 2

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Rev Acta Médica 2021; 22 (2)

Diagnosis of Chlamydia trachomatis and urogenital mycoplasmas in patients with cervicitis and pelvic inflammatory disease

Isaac EY, Zayas IA, Marrero DC, Escobar YNV, Mariño CMC

Language: Spanish
References: 23
Page:
PDF size: 142.34 Kb.


ABSTRACT

Introduction: Cervicitis and Pelvic Inflammatory Disease contribute to high morbidity in the female population, particularly in fertile and active working age women. Both entities can be caused by Chlamydia trachomatis and urogenital mycoplasmas.
Objective: To identify the frequency of Chlamydia trachomatis and urogenital mycoplasmas, as well as the association with other microorganisms in cervicovaginal samples from patients with cervicitis and pelvic inflammatory disease, treated at Dr. Juan Bruno Zayas Alfonso General Hospital in Santiago de Cuba, from May to October 2018.
Methods: An observational, descriptive and cross-sectional study was carried out in 190 women. The studied population had cervicitis and Pelvic Inflammatory Disease with positive cervicovaginal samples for Chlamydia trachomatis and urogenital mycoplasmas, who were treated at Dr. Juan Bruno Zayas Alfonso. General Hospital in Santiago de Cuba, from May to October 2018. The data was processed through the SPSS system, summary measures, such as absolute frequency and percentage, were used.
Results: Chlamydia trachomatis, frequently associated with urogenital mycoplasmas, predominated. Other microorganisms such as Candida spp, Trichomona vaginalis and causative agents of bacterial vaginosis such as Gardnerella vaginalis were identified. Vaginal secretions predominated among the symptoms, whose characteristics did not always correspond to the microorganisms present in them.
Conclusions: The high frequency of Chlamydia trachomatis and urogenital mycoplasmas in females with cervicitis and Pelvic Inflammatory Disease, of fertile and active working age women with generally unprotected sexual relations, justifies the need for an early microbiological diagnosis of these infections.


REFERENCES

  1. Aguiar H, González F, Pacheco C, Correia H, Herrera F. Prevalencia deChlamydia trachomatis en mujeres asintomáticas. Rev Obstet Ginecol Venez. 2017[acceso:11/01/2020];77(4):266-70. Disponible en:https://www.researchgate.net/profile/Henry_Aguiar/publication/324832042_Prevalencia_de_Chlamydia_trachomatis_en_mujeres_asintomaticas/links/5ae640620f7e9b9793c7a3c1/Prevalencia-de-Chlamydia-trachomatis-en-mujeresasintomaticas.pdf

  2. Piscopo RC, Guimarães RV, Ueno J, Ikeda F, Bella ZIJ, Girão MJ, Samama M.Increased prevalence of endocervical Mycoplasma and Ureaplasmacolonization in infertile women with tubal factor. JBRA Assist Reprod.2020;24(2):152-7. DOI: https://doi.org/10.35563/rmp.v8i1.9

  3. Cheong HC, Lee CYQ, Cheok YY, Tan GMY, Looi CY, Wong WF.Chlamydiaceae: Diseases in Primary Hosts and Zoonosis. Microorganisms.2019;7(5):146-63. DOI: http://dx.doi.org/10.3390/microorganisms7050146

  4. Zhu H, Shen Z, Luo H, Zhang W, Zhu X. Chlamydia Trachomatis Infection-Associated Risk of Cervical Cancer: A Meta-Analysis. Medicine.2016[acceso:21/05/2020];95(13):e3077. Disponible en:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998531/pdf/medi-95-e3077.pdf

  5. Jutinico Shubach AP, González Devia JL, Sánchez Mora RM. Asociación deHSP60 de Chlamydia trachomatis y desarrollo de cáncer de ovario. Nova.2017[acceso:25/07/2020];15(28):57-68. Disponible en:http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S1794-24702017000200057&lng=en

  6. Di Pietro M, Filardo S, Porpora MG, Recine N, Latino MA, Sessa R.HPV/Chlamydia trachomatis co-infection: metagenomic analysis of cervicalmicrobiota in asymptomatic women Section of Microbiology. NewMicrobiologica. 2018[acceso:06/05/2020];41(1):34-41. Disponible en:http://www.newmicrobiologica.org/PUB/allegati_pdf/2018/1/34.pdf

  7. Marín H, Urquijo MC, Del Puerto A. Infección por Mycoplasma hominis yUreaplasma urealyticum en población femenina de la ciudad de Resistencia,Chaco. Rev. Fac. Med. UNNE. 2018[acceso:21/02/2020];38(2):14-22.Disponible en:http://181.15.198.188/index.php/med/article/download/59/59

  8. Vallely LM, Egli Gany D, Pomat W, Homer C, Guy R, et al. Adversepregnancy and neonatal outcomes associated with Neisseria gonorrhoeae,Mycoplasma genitalium, M. hominis, Ureaplasmaurealyticum and U. parvum:a systematic review and meta-analysis protocol. BMJ Open.2018;8(11):e024175. DOI: http://dx.doi.org/10.1136/bmjopen-2018-024175

  9. López Pérez M, Palma Mora S, García Gómez D. Infeccionescervicovaginales en pacientes sintomáticas atendidas en la Consulta externade Ginecología. Acta Médica del Centro. 2020[acceso:25/07/2020];14(1):53-9.Disponible en: https://www.medigraphic.com/pdfs/medicadelcentro/mec-2020/mec201f.pdf

  10. Peña Mantilla AB, Bonachea Peña RR, Beltrán Molina EM, EchemendíaMarrero D, Fernández Caballero Z, Álvarez Farfán M. Daños y consecuenciasde Chlamydia trachomatis en mujeres infértiles. Rev Cubana Obstet Ginecol.2019[acceso:26/07/2020];45(2):e449. Disponible en:http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-00X2019000200001&lng=es

  11. Rodríguez Pendás BV, Reyes Rodríguez H, Vázquez Niebla JC, CabreraGámez M, González Hernández O, Menéndez Castillo AM. Micoplasmahominis yUreaplasmaspp en mujeres que consultan por infertilidad. Rev CubanaEndocrinol. 2019[acceso:26/07/2020];30(3):e211. Disponible en:http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1561-29532019000300005&lng=es

  12. Liang YY, Zhai HY, Li ZJ, Jin X, Chen Y, Chen SP. Prevalence ofUreaplasmaurealyticum, Chlamydia trachomatis, Neisseria gonorrhoeae andherpes simplex virus in Beijing, China. Epidemiology and Infection.2019;147:e59,1–5. DOI: https://doi.org/10.1017/S0950268818003163

  13. Leli C, Mencacci A, Latino MA, Clerici P, Rassu M, Perito S, et al. Prevalenceof cervical colonization by Ureaplasmaparvum, Ureaplasmaurealyticum,Mycoplasma hominis and Mycoplasma genitalium in childbearing age women bya commercially available multiplex real-time PCR: An Italian observationalmulticentre study. JMII. 2018;51:220-5. DOI:http://dx.doi.org/10.1016/j.jmii.2017.05.004

  14. Cedeño M, Marín J, Espino C, De Moreno N. Incidencia de Chlamydiatrachomatis y micoplasmas genitales en adolescentes de 10 a 19 años delCentro de Atención Integral del Adolescente de Colón, en los meses de julio aseptiembre del año 2018. Visión Antataura. 2020[acceso:19/07/2020];4(1):25-35. Disponible en:http://revistas.up.ac.pa/index.php/antataura/article/view/1394

  15. De La Cruz Grimaldo EN, Márquez Guzmán CJ, Zambrano Cerna LD.Chlamydia trachomatis en mujeres en etapa reproductiva con actividadsexual. Revméd panacea. 2019[acceso:11/01/2020];8(1):4-11. Disponible en:http://revistas.unica.edu.pe/index.php/panacea/article/download/9/9

  16. Hoenderboom BM, Van Benthem BH, Van Bergen JE, Dukers Muijrers NH,Götz HM, Hoebe CJ, et al. Relation between Chlamydia trachomatis infectionand pelvic inflammatory disease, ectopic pregnancy and tubal factorinfertility in a Dutch cohort of women previously tested for chlamydia in achlamydia screening trial. Sex Transm Infect.2019[acceso:23/03/2020];95(4):300-6. Disponible en:https://sti.bmj.com/content/sextrans/95/4/300.full.pdf

  17. Moore MS, Golden MR, Scholes D, Kerani RP. Assessing Trends in ChlamydiaPositivity and Gonorrhea Incidence and Their Associations with the Incidenceof Pelvic Inflammatory Disease and Ectopic Pregnancy in Washington State,1988-2010. Sex Transm Dis. 2016[acceso:12/06/2020];43(1):2-8. Disponibleen: https://pubmed.ncbi.nlm.nih.gov/26656441/

  18. Li W, Liu LL, Luo ZZ, Han CY, Wu QH, Zhang L, et al. Associations ofsexually transmitted infections and bacterial vaginosis with abnormal cervicalcytology: A cross-sectional survey with 9090 community women in China.PLoSOne. 2020;15(3):e0230712. DOI:https://doi.org/10.1371/journal.pone.0230712

  19. Kim HS, Kim TJ, Lee IH, Hong SR. Associations between sexually transmittedinfections, high-risk human papillomavirus infection, and abnormal cervical Papsmear results in OB/GYN outpatients. J Gynecol Oncol. 2016;27(5):e49. DOI:https://doi.org/10.3802/jgo.2016.27.e49

  20. Yea Seul H, Sang Hoon C, Ji Young C, Tae-Jung S. Clinical Effects ofUreaplasmaurealyticum Colonization in Maternal Vaginal Fluid at SecondTrimester on Neonatal Outcomes of Premature Infant ≤35 Weeks’ GestationalAge Department of Pediatrics, Kangnam Sacred Heart Hospital, HallymUniversity Medical Center, Seoul, Korea. Neonatal Med. 2017;24(3):123-8. DOI:https://doi.org/10.5385/nm.2017.24.3.123

  21. El-Dien Hosny A, El-khayat W, Kashefa MT, Fakhryc MN. Associationbetween preterm labor and genitourinary tract infections caused byTrichomonas vaginalis, Mycoplasma hominis, Gram-negative bacilli andcoryneforms. Journal of the Chinese Medical Association.2017[acceso:29/05/2020];80:575-81. Disponible en:https://www.sciencedirect.com/science/journal/17264901

  22. Barraza Guimarrea NL, Ayala peralta F, Izaguirre Lucano H, Luna FigueroaA, Carrazanaasmat C. Características de vulvovaginitis por Candida albicans enmujeres en edad reproductiva. Rev Peru Investig Mater Perinat.2019[acceso:11/01/2020];8(1):8-12. Disponible en: https://investigacionmaternoperinatal.inmp.gob.pe/index.php/rpinmp/article/view/133/140

  23. Fürnkranz U, Henrich B, Walochnik J. Mycoplasma hominis impacts geneexpression in Trichomonas vaginalis. Parasitol Res.2018[acceso:11/01/2020];117:841-7. Disponible en:https://link.springer.com/content/pdf/10.1007/s00436-018-5761-6.pdf




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