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Instituto Nacional de Salud Pública

2022, Number 4

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salud publica mex 2022; 64 (4)

Prevalence of anti-SARS-CoV-2 antibodies and associated factors in healthcare workers of a Mexican Covid-19 hospital

Herrera-Ortiz A, Rojas-Delgado HU, García-Cisneros S, Xibille-Friedmann DX, Martínez-Barnetche J, Olamendi-Portugal M, González-Sánchez HM, Sánchez-Alemán MÁ

Language: English
References: 37
Page: 348-356
PDF size: 268.48 Kb.


ABSTRACT

Objective. To determine the prevalence of SARS-CoV-2 antibodies among healthcare workers (HCW) and to identify factors associated with infection. Materials and methods. A cross-sectional study was conducted in a Covid-19 hospital in Morelos, Mexico. Antibodies against SARS-CoV-2 spike and nucleocapsid proteins were detected by ELISA. A bivariate and multivariable Poisson regression model were performed to identify factors associated with infection. Results. Among all participants, 31% had anti-SARS-CoV-2 antibodies, while only 13.1% had reported a history of positive RT-PCR. Individuals who reported cohabiting with someone with Covid-19, and those who had a previous RT-PCR test, were more likely to be seropositive. Laboratory personnel had the lowest seroprevalence (12.0%), while social workers had the highest (35.7%). Conclusions. The results of this study show the seroprevalence of SARS-CoV-2 antibodies among HCW in a hospital in Mexico, and underline the importance of serological tests for a better estimate of prevalence in health systems where only symptomatic cases are recorded.


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