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2021, Number 1

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Invest Medicoquir 2021; 13 (1)

Stevens-Jonhson syndrome secondary to dimenhydrate in pediatric age

Muiños MC, Perez VA, Durán MK
Full text How to cite this article

Language: Spanish
References: 14
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PDF size: 391.06 Kb.


Key words:

Stevens-Johnson syndrome, hypersensitivity, skin disease, dimenhydrate, medicines.

ABSTRACT

Stevens-Johnson syndrome is a rare and serious acute inflammatory disease, caused by a hypersensitivity reaction, secondary to medication or infection intake, which affects the skin and mucous membranes, producing characteristic lesions of reactive dermatoses with the presence of vesicles and / or blisters, caused by keratinocyte apoptosis. Its association with dimenhydrate is uncommon. The case of a 9-year-old schoolgirl is presented, with a clinical diagnosis of Stevens-Johnson syndrome, with cutaneous, ocular, genital and oral mucosal manifestations, which began after intake of dimenhydrate. It was maintained with a protocol of care that included the proscription of the drug and the beginning of pharmacological and non-pharmacological measures; After 10 days of hospitalization, the patient progresses satisfactorily without complications during her hospital stay.


REFERENCES

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Invest Medicoquir. 2021;13