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Revista Mexicana de Ortopedia Pediátrica

ISSN 2007-087X (Print)
Órgano Oficial de la Sociedad Mexicana de Ortopedia Pediátrica
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2022, Number 1-3

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Rev Mex Ortop Ped 2022; 24 (1-3)

Antibiotic prophylaxis in pediatric orthopaedic surgery applying American Society of Health-System Pharmacists guidelines

Castro-Núñez KL, Hernández-Gómez C, Haces-García F, Ordaz-Robles T
Full text How to cite this article 10.35366/106975

DOI

DOI: 10.35366/106975
URL: https://dx.doi.org/10.35366/106975

Language: Spanish
References: 13
Page: 19-23
PDF size: 161.39 Kb.


Key words:

Antibiotic prophylaxis, surgical site infection, pediatric orthopaedic surgery.

ABSTRACT

Objective: To determine if the use of limited antibiotic prophylaxis reduces surgical site infections in pediatric orthopaedic surgery. Material and methods: Analytic comparative study. N = 1,077 patients who underwent pediatric orthopaedic surgery at Shriners Hospital for Children Mexico from March 2018 to February 2021. Group A: 359 receiving limited antibiotic prophylaxis and group B: 718 receiving conventional antibiotic prophylaxis. Assessing their postoperative follow-up during first year in search of surgical site infection. Results: Group A: 176 (49%) female and 183 (51%) male, five years old; 221 (68%) patients underwent soft tissue surgery and 138 (32%) patients used surgical implants. Group B: 365 (50.83%) female and 353 (49.16%) male, six years old; 442 (62%) patients underwent soft tissue surgery and 276 (38%) patients used surgical implants. The antibiotic used was cephalothin in 1,026 (95.2%) patients in both groups and clindamycin in 51 (4.7%). Group B was extended antibiotic up to 7 days postoperatively. No surgical site infections were reported. Conclusions: Limited antibiotic prophylaxis does not modify the risk of surgical site infection compared to conventional prophylaxis, and is considered a safe strategy.


REFERENCES

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  2. Dimopoulou A, Kourlaba G, Psarris A, Coffin S, Spoulou V, Zaoutis T. Perioperative antimicrobial prophylaxis in pediatric patients in Greece: Compliance with guidelines and impact of an educational intervention. J Pediatr Surg. 2016; 51(8): 1307-1311.

  3. Gómez-Romero FJ, Navarro-Gracia F. Prevención de la infección del sitio quirúrgico: análisis y revisión narrativa de las guías de práctica clínica. Cir Esp. 2017; 95(9): 490-502. Disponible en: https://doi.org/10.1016/j.ciresp.2017.09.004

  4. Giordano M, Squillace L, Pavia M. Appropriateness of surgical antibiotic prophylaxis in pediatric patients in Italy. Infect Control Hosp Epidemiol. 2017; 38(7): 823-831.

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  10. Rangel SJ, Fung M, Graham DA, Ma L, Nelson CP, Sandora TJ. Recent trends in the use of antibiotic prophylaxis in pediatric surgery. J Pediatr Surg. 2011; 46(2): 366-371.

  11. Perotti LR, Abousamra O, Rogers KJ, Miller F, Sees JP. Prophylactic antibiotics in soft-tissue procedures in children with cerebral palsy. J Child Orthop. 2018; 12(3): 279-281.

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  13. Malone SM, Seigel NS, Newland JG, Saito JM, McKay VR. Understanding antibiotic prophylaxis prescribing in pediatric surgical specialties. Infect Control Hosp Epidemiol. 2020; 41(6): 666-671.



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Rev Mex Ortop Ped. 2022;24