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Colegio de Medicina Interna de México.

2022, Number 4

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Med Int Mex 2022; 38 (4)

Acute kidney injury in hepatic cirrhosis

Rodríguez-Aguilar EF, Sánchez-Herrera D, Mellado-Orellana R, García-Juárez I

Language: Spanish
References: 24
Page: 847-858
PDF size: 241.33 Kb.


ABSTRACT

Acute kidney injury is a frequent complication in patients with advanced liver cirrhosis. About 20-50% of patients hospitalized for decompensation of cirrhosis have kidney injury on admission or evolution during hospitalization. The differential diagnosis among the different causes of acute kidney injury is essential and the treatment differs completely among each one. A better prognosis has been observed in patients with parenchymal nephropathy and a poorer prognosis in acute kidney injury-related infections and hepatorenal syndrome. Finally, there are consistent data showing that some urine biomarkers, particularly NGAL (neutrophil gelatinase- associated lipocalin) can be useful in clinical practice for differential diagnosis. Patients with acute kidney injury have a poor short-term prognosis, especially patients with hepatorenal syndrome, so these patients should be selected for liver transplantation, therefore eligible candidates should be identified early and referred for liver transplantation evaluation.


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