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Revista Biomédica

Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán
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2022, Number 3

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Rev Biomed 2022; 33 (3)

The SARS-CoV-2 early infections phylogeny as an example of the misinterpreting of phylogenies in epidemiology

Colunga-Salas P, Segura-Trejo D, Miranda-Caballero CI, Sánchez-Montes S, Arteaga-Vázquez M, Becker I
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Language: English
References: 4
Page: 85-87
PDF size: 99.92 Kb.


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Dear Editor,
Taking into consideration the underlying concept of molecular epidemiology as the axis of epidemiology, uniting insights at the molecular level and the understanding of diseases at the population and geographic levels, it is not surprising that the use of phylogenetic approaches to understand and to determine the geographic origin and traceability of animal cases, including humans, has increased over the years. However, methodological misconceptions, arisen because of an indiscriminate use of phylogenetic approaches, in many cases have led to wrong conclusions regarding the ancestors-descendants relationships that can be extrapolated to geographic scales.


REFERENCES

  1. Wang X, King Jordan I, Mayer LW. A phylogeneticperspective on molecular epidemiology. Second Edi. In:Tang Y-W, Liu D, Schwartzman J, Sussman M, PoxtonI, editors. Molecular Medical Microbiology. 2nd ed.Elsevier Ltd; 2014. pp. 517–536.

  2. Lam TT-Y, Hon C-C, Tang JW. Use of phylogenetics inthe molecular epidemiology and evolutionary studies ofviral infections. Crit Rev Clin Lab Sci. 2010;47: 5–49.https://doi.org/10.3109/10408361003633318

  3. Henning W. Phylogenetic systematics. Annu RevEntomol. 1965;10: 97–116. https://doi.org/10.1146/annurev.en.10.010165.000525

  4. Colunga-Salas P, Hernández-Canchola G. Bats andhumans during the SARS-CoV-2 outbreak: The case ofbat-coronaviruses from Mexico. Transbound Emerg Dis.2021;68: 987–992. https://doi.org/10.1111/tbed.13751




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Rev Biomed. 2022;33