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Anales de Otorrinolaringología Mexicana

2022, Number 3

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Otorrinolaringología 2022; 67 (3)

Acromegaly and airway obstruction

Osorio-Anaya S, Uribe-Escobar A, González-Orozco A

Language: Spanish
References: 12
Page: 217-221
PDF size: 192.54 Kb.


ABSTRACT

Background:Acromegaly is a rare disease resulting from growth hormone secreting pituitary macroadenomas. Clinical manifestations are variable and airway compromise tends to be infrequent leading to diagnostic delay and early treatment.
Case Report: A 52-year-old female patient with acromegaly, presenting laryngeal symptoms with endoscopic findings of supraglottic edema and airway obstruction requiring surgical intervention with blue-laser supraglottoplasty, with adequate clinical evolution.
Conclusions: Clinical and airway manifestations in patients with suspicion or diagnosis of acromegaly have to be recognized early to ensure adequate and timely treatment.


REFERENCES

  1. Vilar L, Vilar CF, Lyra R, Lyra R, Naves LA. Acromegaly:clinical features at diagnosis. Pituitary 2017; 20 (1): 22-32.doi:10.1007/s11102-016-0772-8.

  2. Melmed S. Medical progress: acromegaly. N Engl J Med2006; 355 (24): 2558-73. doi: 10.1056/NEJMra062453.

  3. Molitch ME. Clinical manifestations of acromegaly. EndocrinolMetab Clin North Am 1992; 21 (3): 597-614.

  4. Ribeiro-Oliveira A Jr, Barkan A. The changing face ofacromegaly--advances in diagnosis and treatment. NatRev Endocrinol 2012; 8 (10): 605-611. doi:10.1038/nrendo.2012.101.

  5. Lerat J, Lacoste M, Prechoux JM, Aubry K, Nadalon S, LyKH, et al. An uncommon case of dyspnea with unilaterallaryngeal paralysis in acromegaly. Auris Nasus Larynx 2016;43 (1): 105-7. doi: 10.1016/j.anl.2015.06.001.

  6. Smaily H, Matar N. Laryngeal manifestations in acromegaly:a systematic review of the literature. Acta Otolaryngol CaseRep 2020; 5 (1): 57-63. https://doi.org/10.1080/23772484.2020.1809421.

  7. Murrant NJ, Gatland DJ. Respiratory problems in acromegaly.J Laryngol Otol 1990; 104: 52-55. doi: 10.1017/s0022215100111806.

  8. Saussez S, Mahillon V, Chantrain G, Thill MP, Lequeux T.Acromegaly presented as a causa of laryngeal dyspnea.Auris Nasus Larynx 2007; 34: 541-543. doi: 10.1016/j.anl.2006.11.014.

  9. Siegler J. Acromegaly associated with laryngeal obstruction.J Laryng 1952; 66: 620. doi:10.1017/S0022215100048209.

  10. Bhatia ML, Misra SC, Prakash J. Laryngeal manifestationsin acromegaly. J Laryngol Otol 1966; 80 (4): 412-7. doi:10.1017/s0022215100065440.

  11. Morewood DJ, Belchetz PE, Evans CC, Whitehouse GH. Theextrathoracic airway in acromegaly. Clin Radiol 1986; 37 (3):243-246. doi: 10.1016/s0009-9260(86)80327-0.

  12. Williams RG, Richards SH, Mills RG, Eccles R. Voice changesin acromegaly. Laryngoscope 1994; 104 (4): 484-7. doi:10.1288/00005537-199404000-00015.




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