Ramos RMA, Ruiz RA, López RY, Verde CL

Language: Spanish
References: 7
Page: 1-5
PDF size: 241.87 Kb.

ABSTRACT

Introduction: Health professionals are constantly exposed to stressful situations. In particular, nurses, dedicated to the care of critical patients, are more affected by work stress, which negatively impacts their mental health and predisposes them to infections. This shows the close psychoneuroimmunendocrine interrelation.
Objective: To describe the clinical and immunological consequences of chronic work stress in a intensivist nurse.
Case report: The 39-year-old patient had recurrent varicella zoster infections as well as skin furunculosis, urinary tract infections, pneumonia, and vaginal candidiasis in one year. Marked neutropenia, monocytopenia, and hypogammaglobulinemia were noted. Flow cytometry showed a decrease in CD4 + T helper lymphocytes and CD19 + B lymphocytes. Immunodeficiency secondary to chronic work stress and severe depression was diagnosed. Immunomodulatory therapy with subcutaneous transfer factor (Hebertrans) and vitamin therapy improved her immunity.
Conclusions: Immunocompetent health workers exposed to high levels of stress, the presence of recurrent or multiple infections of varied etiology in a short time may be associated with potentially reversible immunodeficiency if the cause is controlled or eliminated.

REFERENCES

1. Carmiña García CH. Estrés crónico: ejemplo de interacción entre sistemas nervioso, inmuno y endocrino. Rev. Cs. Farm y Bioq. 2018[acceso: 14/07/2020];6(2):97-110. Disponible en: http://www.scielo.org.bo/scielo.php?script=sci_arttext&pid=S2310-02652018000200010&lng=es

2. Banegas Cardero A, Sierra Calzado L. Variables bioquímicas e inmunológicas en pacientes con estrés agudo o crónico. MEDISAN. 2017[acceso: 07/08/2019];21(8):1038. Disponible en: http://www.medisan.sld.cu/index.php/san/article/view/1373

3. Kotekewis K, Ribeiro Renata P, Ribeiro Benedita GA, Martins Julia T. Enfermedades crónicas no transmisibles y el estrés de los trabajadores de enfermería de unidades quirúrgicas. Enferm Glob. 2017;16(46):295-314. http://dx.doi.org/10.6018/eglobal.16.2.252581

4. Rendón Montoya MS, Peralta Peña SL, Hernández Villa EA, Hernández Pedroza RI, Vargas MR, Favela Ocaño MA. Síndrome de Burnout en el personal de enfermería de unidades de cuidado crítico y de hospitalización. Enferm Glob. 2020;19(3):479-506. https://doi.org/10.6018/eglobal.398221

5. Pérez de Alejo Rodríguez LM, Moré Chang CX, González Álvarez Y, Alemán Zamora A. La psiconeuroendocrinoinmunología: reclamo de una visión integral en los estudios médicos. EDUMECENTRO. 2019[acceso: 22/07/2020];11(3):254-61. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S2077-28742019000300254&lng=es

6. Banegas Cardero A, Sierra Calzado L, Vidal Anido H, Rabionet Joa B. Variables hematológicas en pacientes con neurosis y reacción situacional por estrés. MEDISAN. 2016[acceso: 07/12/2019];20(4):462-71. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029-30192016000400006&lng=es

7. Gerada C, Campbell TM, Kennedy JJ, McSharry BP, Steain M, Slobedman B, et al. Manipulation of the innate immune response by varicella zoster virus. Front. Immunol. 2020;11:1. https://10.3389/fimmu.2020.00001