medigraphic.com
ISSN 1561-3046 (Electronic)

2021, Number 2

<< Back Next >>

Rev Cub Med Mil 2021; 50 (2)

Potential for malignant transformation of whitish oral lesions

Figueroa PY, Pérez AD, Borges GT, Ortiz DLA, Cabrera GAG, Jiménez RY

Language: Spanish
References: 16
Page:
PDF size: 272.05 Kb.


ABSTRACT

Introduction: Potentially malignant whitish oral lesions are a recognizable group of mucosal diseases that precede the appearance of invasive cancers of the oral cavity.
Objective: To determine the potential malignant transformation of whitish lesions in the oral cavity.
Methods: An observational, descriptive and cross-sectional study was carried, from January 2016 to January 2020, of all patients who attended the Maxillofacial Surgery service with whitish oral lesions. The variables used were: age, sex, risk factors, time of evolution, and site of the lesion, histological diagnosis and potential for malignant transformation. To explore the association between categorical variables, the Chi square distribution was used.
Results: Lesions with the potential for malignant transformation were found in 24 % of those over 50 years of age, in 24,3 % of men and in 40 % of patients with actinic cheilitis. 83,3% were leukoplakia, and among them 20 % with the potential for malignant transformation.
Conclusions: Leukoplakia was the most common histological diagnosis. Lesions with the potential for malignant transformation increased with age, were greater in men and in actinic cheilitis patients. The anatomical sites in which they appeared most were on the soft palate and upper lip and among the risk factors with the greatest association was sun exposure.


REFERENCES

  1. Mortazavi H, Safi Y, Baharvand M, Jafari S, Anbari F, Rahmani S. Oral White Lesions: An Updated Clinical Diagnostic Decision Tree. Dent J (Basel). 2019 [acceso: 06/10/2020];7:15-21. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473409/

  2. Lodi G, Franchini R, Warnakulasuriya S, Varoni EM, Sardella A, Kerr AR, et al. Interventions for treating oral leukoplakia to prevent oral cancer. Cochrane Database Syst Rev M. 2016 [acceso: 24/09/2016];7: 2-23. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457856/pdf/CD001829.pdf

  3. Miyazaki H, Jones JA, Beltrán Aguilar ED. Surveillance and monitoring of oral health in elderly people. International Dental Journal. 2017[acceso: 26/09/2020]; 67: 34-41. Disponible en: https://onlinelibrary.wiley.com/doi/full/10.1111/idj.12348

  4. Kovacevic D. Predictors of oral mucosal lesions among removable prosthesis wearers. Periodicum Biologorum. 2017 [acceso: 26/09/2020];119(3):181-7. Disponible en: https://hrcak.srce.hr/file/277655

  5. Choufani A, Folliguet M, Chahine N, Rammal S, Doumit M. Prevalence of oral Mucosal Lesions Among the Institutionalized Elderly Population in Lebanon. Gerontol Geriatr Med. 2020 [acceso: 26/09/2020];6:[aprox. 10pant.]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339905/

  6. Castelnaux Martínez M, Montoya Sánchez I, Serguera Batista Y, Giraldo Moran RM, Pérez Rosabal A. Caracterización clínica y epidemiológica de pacientes con leucoplasia bucal. MEDISAN ;2020. [acceso: 14/10/2020]; 24(1):4-15. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029-30192020000100004&lng=es

  7. Warnakulasuriya S. Clinical features and presentation of oral potentially malignant disorders. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 [acceso: 16/10/2020];125(6):582-90. Disponible en: https://www.oooojournal.net/action/showPdf?pii=S2212-4403%2818%2930854-X

  8. Speight PM, Khurram SA, Kujan O. Oral potentially malignant disorders: risk of progression to malignancy. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018[acceso: 16/10/2020];125(6):612-27. Disponible en: https://www.oooojournal.net/article/S2212-4403%2817%2931248-8/fulltext

  9. Awadallah M, Idle M, Patel K, Kademani D. Management update of potentially premalignant oral epithelial lesions. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 [acceso: 16/10/2020];125(6):628-36. Disponible en: https://www.oooojournal.net/article/S2212-4403%2818%2930848-4/fulltext

  10. Müller S. Oral epithelial dysplasia, atypical verrucous lesions and oral potentially malignant disorders: focus on histopathology. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 [acceso: 26/09/2020];125(6):591-602. Disponible en: https://www.oooojournal.net/article/S2212-4403%2818%2930083-X/fulltext

  11. Estrada Pereira GA, Márquez Filiu M, Hernández Álvarez G, Oliveros Noriega-Roldán S. Identificación del papilomavirus humano en la leucoplasia bucal. MEDISAN. 2013 [acceso: 26/09/2020]; 17(6):944-9. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029-30192013000600009&lng=es

  12. Sánchez M P, Vázquez Cruz C, Sánchez S. El envejecimiento: un breve relato desde un enfoque molecular. RD-ICUAP. Revista Instituto de Ciencias de la Benemérita Universidad Autónoma de Puebla. 2020 [acceso: 26/03/2021]; 6(18): 63-84. Disponible en: http://rd.buap.mx/ojs-dm/index.php/rdicuap/article/view/245/219

  13. Batista Castro Z, González Aguilar V, García Barceló MC, Rodríguez Pérez I, Miranda Tarragó JD, Chica Padilla MA, et al. Evaluación clínico-epidemiológica de trastornos bucales potencialmente malignos en adultos de Montalvo en Ambato, Ecuador. Rev Cubana Estomatol. 2019 [acceso: 20/09/2020]; 56(4):e2121. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75072019000400004&lng=es

  14. Leal Rodríguez MI, Serrano García L, Vinardell Almira LM, Pérez García LA. Consideraciones actuales sobre los factores de riesgo de cáncer bucal. Arch. Hosp. Univ. "Gen. Calixto García”. 2020 [acceso: 31/3/2021]; 8(2):[aprox. 6 p.]. Disponible en: http://www.revcalixto.sld.cu/index.php/ahcg/article/view/501

  15. García San Juan C, Salas Rodríguez M, Gil Milá J. Algunas consideraciones sobre etiología y fisiopatogenia del carcinoma epidermoide bucal. Medisur. 2018[acceso: 31/3/2021];16(1):63-75. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1727897X2018000100010&lng=es

  16. McRae MP, Modak SS, Simmons GW, Trochesset DA, Kerr AR, Thornhill MH, et al. Point-of-care oral cytology tool for the screening and assessment of potentially malignant oral lesions. Cancer Cytopathol. 2020 [acceso: 20/03/2021];128(3):207-20. Disponible en: https://acsjournals.onlinelibrary.wiley.com/doi/full/10.1002/cncy.22236




2020     |     www.medigraphic.com