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ISSN 1561-3046 (Electronic)

2021, Number 2

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Rev Cub Med Mil 2021; 50 (2)

Clinical laboratory parameters in patients with COVID 19

Sánchez VN, Saavedra HD, Hidalgo MCJ, Aguila LM, Abreu GG, Herrera GV, Rodríguez GI

Language: Spanish
References: 15
Page:
PDF size: 336.35 Kb.


ABSTRACT

Introduction: Knowing the alterations in clinical laboratory tests is useful in the diagnosis and progress of patients with COVID-19.
Objective: To describe the clinical laboratory parameters in patients diagnosed with COVID-19.
Methods: Descriptive study in 82 hospitalized patients with COVID-19. The variables analyzed were age, sex, comorbidity, patient report, discharge status, hemoglobin, white blood cell count, absolute neutrophil count, absolute lymphocyte count, platelet count, erythrocyte sedimentation rate, D-dimer, creatinine, urea, alanine aminotransferase, aspartate aminotransferase, γ-glutamyl transpeptidase, alkaline phosphatase, lactate dehydrogenase, neutrophil / lymphocyte and platelet / lymphocyte ratio.
Results: The average age was 55.61 ± 22.04, the majority were female (57.3%), hypertensive (41.5%), 18.3% reported serious and 14.6% died. Advanced age and comorbidity were associated with the severity report. There was a significant decrease in hemoglobin, lymphocytes; elevated erythrocyte sedimentation rate, D-dimer, creatinine, γ-glutamyl transpeptidase, and lactate dehydrogenase, especially in severe patients. The neutrophil / lymphocyte and platelet / lymphocyte ratio warned about the worsening of the patient and the possibility of death.
Conclusions: The patients a mean age of 55.61, female, with arterial hypertension; they were discharged alive, reported as not serious. Mean hemoglobin values ​​decrease, global lymphocyte count, especially in severe patients; increases D-dimer, creatinine, ALT, AST, ALP, GGT, and LD. The neutrophil / lymphocyte and platelet / lymphocyte ratio show high mean values, especially in severely ill patients and in those who died.


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