medigraphic.com
ISSN 2448-8747 (Print)
Publicación cuatrimestral editada por la Secretaría de Salud Jalisco

2022, Number 3

<< Back Next >>

Sal Jal 2022; 9 (3)

Experiencia del Hospital Infantil Universitario de Torreón Coahuila en niños con infección por SARS-Cov-2 y síndromes clínicos asociados

Vázquez-Paredes LA, De Lara-Huerta J, Reyes-Hernández KL, Reyes-Gómez U, Baeza-Casillas JA, Juárez-Campos C, Reyes-Hernández MU, Miguel-Reyes A, González-Ortíz AM, Uribe-Ramos G, Espindola-Díaz A, Mercado-Díaz CU

Language: Spanish
References: 31
Page: 157-170
PDF size: 453.54 Kb.


ABSTRACT

Introduction: COVID-19 disease is caused by the SARS-CoV-2 type coronavirus, the pediatric population can also be aff ected. It presents with diff erent degrees of severity and varied clinical manifestations. Material and methods: Epidemiological study of cases and controls, retrospective, observational, analytical and cross-sectional; carried out at the Children’s Hospital of Torreón, Coahuila Pediatric patients with an RT-PCR test for SARS-COV-2 who required hospitalization in the period from March to December 2020 were included. Laboratory results, signs and symptoms were collected from the fi les upon admission to hospitalization. In addition to obtaining information on the management of patients infected by SARS-COV-2 and associated clinical syndromes. Results: 74 patients were included in the study, aff ected age group were those under 6 years of age. Of the positive cases, 50% (n = 5) presented without association with a characteristic clinical syndrome. The group with confi rmed infection presented a signifi cantly higher frequency of asthenia (p ‹0.01), adynamia (p ‹0.01), alterations to the general state (p ‹0.01) and somnolence (p ‹0.01) compared to the control group. Hemoglobin levels were lower in the infected group (p ‹0.05), the BUN level was signifi cantly elevated in the infected group of 7-17 years (p ‹0.01). No specifi c management was used for the SARSCOV-2 infection. Conclusions: Th e most aff ected age group was 0-6 years. Th e clinical manifestations were nonspecifi c, and the associated syndromes varied.


REFERENCES

  1. Ludvigsson, JF. Systematic review of COVID‐19 in children showmilder cases and a better prognosis than adults. Acta Pediatrica. 2020; https://latinjournal.org/index.php/roh/article/view/951

  2. Surveillances, V. 8, 2020. Th e epidemiological characteristics ofan outbreak of 2019 novel coronavirus diseases (COVID-19)China, 2020. CDC Weekly, 2020; 2: 11322

  3. Schwartz DA. An analysis of 38 pregnant women with COVID-19,their newborn infants, and maternal-fetal transmission ofSARS-CoV-2: maternal coronavirus infections and pregnancyoutcomes. Archives of pathology & laboratory medicine. 2020.

  4. Centers for Disease Control and Prevention. HealthcareProfessionals: Frequently Asked Questions and Answers. 2020.www.cdc.gov/coronavirus/2019-ncov/hcp/faq.html

  5. CDC. Coronavirus Disease 2019 in Children — United States.https://www.cdc.gov/mmwr/Novel_Coronavirus_Reports.html

  6. Asociación Mexicana de Pediatría. Síntesis de la Infección porCOVID-19 del paciente pediátrico en base a la informaciónsurgida de la pandemia.

  7. Secretaría de Salud. Dirección General de Epidemiología.Lineamiento Estandarizado para la Vigilancia Epidemiológica ypor Laboratorio de la Enfermedad Respiratoria Viral. Abril 2020.

  8. Soraya GV, Ulhaq ZS. Crucial laboratory parameters in COVID-19diagnosis and prognosis: An updated meta-analysis. MedicinaClínica (English ed.) 2020; 155(4): 143–51

  9. Ahmad, S, Ahmed RN, Jani P, Ullah M, Aboulgheit H. SARSCoV-2 isolation from an appendix. Journal of surgical casereports, 2020; 8: 245

  10. Ouldali N, Pouletty M, Mariani P, Beyler C, Blachier A, BonacorsiS. et al. Emergence of Kawasaki disease related to SARS-CoV-2infection in an epicentre of the French COVID-19 epidemic:a time-series analysis. Th e Lancet. Child Adolescent health.2020; 4(9): 662–8

  11. Frank C, Almeida T, Marques EA, de Sousa Monteiro Q, Feitoza,P, Borba M, et al. Guillain-Barré Syndrome Associated withSARS-CoV-2 Infection in a Pediatric Patient. Journal of tropicalpediatrics. 2020

  12. De Sousa AK, Magalhães DA, Ferreira J, Barbosa A. SARSCoV-2-mediated encephalitis: Role of AT2R receptors in theblood-brain barrier. Medical hypotheses. 2020; 144: 110213

  13. Lu X, Zhang L, Du H, et al. (2020) SARS-CoV-2 Infection inChildren. N Engl J Med 2020; 382: 1663

  14. Zimmermann P, Curtis N. Coronavirus Infections in ChildrenIncluding COVID-19: An Overview of the Epidemiology,Clinical Features, Diagnosis, Treatment and PreventionOptions in Children. Pediatr Infect Dis J. 2020; 39: 355.

  15. Dong Y, Mo X, Hu Y, et al. Epidemiology of COVID-19Among Children in China. Pediatrics 2020 Jun; 145(6):e20200702.

  16. Viner RM, Mytton OT, Bonell C, et al. Susceptibility toSARS-CoV-2 Infection Among Children and AdolescentsCompared With Adults: A Systematic Review and Metaanalysis.JAMA Pediatr. 2020; 47:65

  17. Hoang A, Chorath K, Moreira A, et al. COVID-19 in 7780pediatric patients: A systematic review. EClinicalMedicine.2020; 24:100433.

  18. Lee B, Raszka WV Jr. COVID-19 Transmission and Children:The Child Is Not to Blame. Pediatrics. 2020; 146: 2-5

  19. Posfay-Barbe KM, Wagner N, Gauthey M, et al. COVID-19in Children and the Dynamics of Infection in Families.Pediatrics 2020; 146

  20. Wu Q, Xing Y, Shi L, et al. (2020) Coinfection and OtherClinical Characteristics of COVID-19 in Children. Pediatrics2020; 146.

  21. Szablewski CM, Chang KT, Brown MM, et al. SARSCoV-2 Transmission and Infection Among Attendees of anOvernight Camp - Georgia, June . MMWR Morb MortalWkly Rep. 2020; 69: 1023

  22. Goldstein E, Lipsitch M, Cevik M. On the eff ect of age on thetransmission of SARS-CoV-2 in households, schools and thecommunity. J Infect Dis. 2021;223(3):362-9

  23. Heald-Sargent T, Muller WJ, Zheng X, Rippe J, Patel AM, KociolekL. et al Age-Related Diff erences in Nasopharyngeal Severe AcuteRespiratory Syndrome Coronavirus 2 (SARS-CoV-2) Levelsin Patients With Mild to Moderate Coronavirus Disease 2019(COVID-19). JAMA Pediatr. 2020; 174: 902

  24. Hurst JH, Heston SM, Chambers HN, et al. SARS-CoV-2Infections Among Children in the Biospecimens fromRespiratory Virus-Exposed Kids (BRAVE Kids) Study. ClinInfect Dis. 2020 disponible en: https://www.medrxiv.org/content/medrxiv/early/2020/09/01/2020.08.18.20166835.full.pdf

  25. Laws RL, Chancey RJ, Rabold EM, Chu TV, Lewis MN, FajansM. et al. a Symptoms and Transmission of SARS-CoV-2 AmongChildren - Utah and Wisconsin, March-May . Pediatrics. 2020;147(1): e2020027268

  26. Danis K, Epaulard O, Bénet T, Gaymard A, Campoy S,Botelho-Nevers et al. Cluster of Coronavirus Disease 2019(COVID-19) in the French Alps, February 2020. Clin InfectDis 2020; 71: 825

  27. Heavey L, Casey G, Kelly D, McDarby G. No evidence ofsecondary transmission of COVID-19 from children attendingschool in Ireland, . Euro Surveill 2020; 25: 21

  28. Lopez AS, Hill M, Antezano J, et al. Transmission Dynamicsof COVID-19 Outbreaks Associated with Child Care Facilities- Salt Lake City, Utah, April-July 2020. MMWR Morb MortalWkly Rep 2020; 69: 1319.

  29. Qiu H, Wu J, Hong L, et al. Clinical and epidemiological featuresof 36 children with coronavirus disease 2019 (COVID-19) inZhejiang, China: an observational cohort study. Lancet InfectDis 2020; 20: 689.

  30. Kelvin AA, Halperin S. COVID-19 in children: the link in thetransmission chain. Lancet Infect Dis 2020; 20: 633.

  31. Dirección general de epidemiología de la Secretaria de Salud.Datos abiertos Covid-19. Secretaria de Salud 2021.




2020     |     www.medigraphic.com