Hernandez FOJ, Arteaga RC

Language: English
References: 4
Page: 1-3
PDF size: 187.86 Kb.

Text Extraction

Dear editor

We would like to contribute with an interesting clinical finding, of an study from southern Brazilian that may highlight the discussion about the importance of stroke and Human Immunodeficiency virus (HIV). In patients with Acquired Immunodeficiency Syndrome (AIDS), cerebrovascular disease (CVD) occurs more frequently than in the rest of the population. CVD is an important cause of morbidity/mortality in patients with AIDS, and there are data in the literature that suggest an increase on CVD in patients with AIDS, in contrast to the decrease on CVD rates in general.
HIV is neurotropic, neuroinvasive and neurovirulent, and it is associated with cerebral arteriopathy characterized by occlusive and aneurysmal lesions, with endothelial dysfunction and arterial inflammation as predisposing factors for the atherosclerotic process.

REFERENCES

1. Mapoure YN, Nkongni IN, Luma HN, Ngahane BH, Barla E, Ngwane S, et al. Incidence des accidents vasculaires cérébraux chez les patients VIH positifs sous traitement antirétroviral au long court [Incidence of strokes in HIV-positive patients treated with long term antiretroviral treatment]. Pan Afr Med J. 2016;24:45. DOI: http://doi.org/10.11604/pamj.2016.24.45.8013

2. Edwards NJ, Grill MF, Choi HA, Ko NU. Frequency and Risk Factors for Cerebral Arterial Disease in a HIV/AIDS Neuroimaging Cohort. Cerebrovasc Dis. 2016;41:170-76. DOI: http://doi.org/10.1159/000442755

3. Shah ASV, Stelzle D, Lee KK, Beck EJ, Alam S, Clifford S, et al. Global Burden of Atherosclerotic Cardiovascular Disease in People Living With HIV: Systematic Review and Meta-Analysis. Circulation. 2018;138:1100-12. DOI: http://doi.org/10.1161/CIRCULATIONAHA.117.033369

4. Yang HY, Beymer MR, Suen SC. Chronic Disease Onset Among People Living with HIV and AIDS in a Large Private Insurance Claims Dataset. Sci Rep. 2019;9(1):18514. DOI: http://doi.org/10.1038/s41598-019-54969-3