medigraphic.com
SPANISH

Revista Cubana de Pediatría

ISSN 1561-3119 (Electronic)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2021, Number 2

<< Back Next >>

Rev Cubana Pediatr 2021; 93 (2)

Asthma and obesity in pediatrics

Abreu-Suárez G, Lorenzo Bobea-Mota A, Portuondo-Leyva R, Araujo-Herrera O, Brito-Portuondo CA
Full text How to cite this article

Language: Spanish
References: 29
Page: 1-12
PDF size: 454.34 Kb.


Key words:

asthma, asthma control, obesity, dyslipidemia, diabetes.

ABSTRACT

Introduction: The association of asthma and obesity has increased its prevalence in recent years.
Objectives: Characterize asthmatic children and adolescents with associated obesity.
Methods: Descriptive, cross-sectional and prospective research, 2017 - 2018, Pneumology Service, Centro Habana University Pediatric Hospital. 43 asthmatic patients from 5 to 18 years old with associated exogenous obesity were assessed. Age, sex, family history of asthma and obesity, severity and degree of asthma control were studied. Studies were conducted to evaluate lipid and carbohydrate metabolism.
Results: Age distribution was similar (schoolers, early and late adolescence), predominated male sex in schoolchildren (11 of 16 - 68.7 %) and the female in late adolescence (12 of 15 -80 %). Family history of obesity was reported in 5 patients (11.6 %) and obesity-associated asthma in 26 (60.5%); most had mild persistent asthma (38 -88.4 %) poorly controlled: 28 uncontrolled (65.1 %) and 10 partially controlled (23.3 %). Two patients had carbohydrate intolerance (4.7 %), one of them with insulin resistance. Dyslipidemia was the most common metabolic disorder: serum cholesterol increased in 23 - 53.5 %, high LDLc in 13 - 30.2 %, and low HDLc in 10 - 23.3 %.
Conclusions: Asthmatic children with a family history of obesity are also at high risk of being obese, which can make difficult to control asthma; metabolic alterations are common in them.


REFERENCES

  1. Gross E, Lee DS, Hotz A, Ngo KC, Rastogi D. Impact of Obesity on Asthma Morbidity During a Hospitalization. Hospital Pediatr. 2018;8(9):538-46. doi: https://doi.org/10.1542/hpeds.2017-0265Gross

  2. Borgmeyer A, Ercole PM, Niesen A, Strunk RC. Lack of Recognition, Diagnosis, and Treatment of Overweight/Obesity in Children Hospitalized for Asthma. Hospital Pediatr. 2016;6(11):667-76. doi: 10.1542/hpeds.2015-0242

  3. Vijayakanthi N, Greally JM, Rastogi D. Pediatric Obesity-Related Asthma: The Role of Metabolic Dysregulation. Pediatrics. 2016;137(5):e2 0150812. doi: 10.1542/peds.2015-0812

  4. Yawn BP, Rank MA, Bertram SL, Wollan PC. Obesity, low levels of physical activity and smoking present opportunities for primary care asthma interventions: an analysis of baseline data from The Asthma Tools Study. Primary Care Respirator Med. 2015;25:15058. doi:10.1038/npjpcrm.2015.58

  5. Umlawska W. Adipose tissue content and distribution in children and adolescents with bronchial asthma. Respirator Med. 2015;109:200-7. doi: http://dx.doi.org/10.1016/j.rmed.2014.11.006

  6. Arteaga-Solis E, Kattan M. Obesity in asthma: Location or hormonal consequences? J Allergy Clin Immunol. 2014;133:1315-6. doi: http://dx.doi.org/10.1016/j.jaci.2014.01.036

  7. Pijnenburg MW, Fleming L. Advances in understanding and reducing the burden of severe asthma in children. Lancet Respir Med. 2020;8(10):1032-44. doi: https://doi.org/10.1016/S2213-2600(20)30399-4

  8. Castro-Rodríguez J. Relación entre obesidad y asma. Arch Bronconeumol. 2007;43(3):171-5. doi: 10.1157/13099535

  9. World Health Organization. Preventing chronic diseases: a vital investment. Geneva: WHO; 2005 [acceso 15/12/2019] Disponible en: https://www.who.int/chp/chronic_disease_report/en/

  10. Trunk-Black Juel C, Ali Z, Nilas L, Ulrik CS. Asthma and obesity: does weight loss improve asthma control? a systematic review. J Asth Allerg. 2012;5:21-6. doi: http://dx.doi.org/10.2147/JAA.S32232

  11. Vázquez-Tantas AM. Asociación entre sobrepeso/obesidad y asma en niños [tesis]. Trujillo, Perú: Universidad Nacional; 2019 [acceso 15/09/2020]. Disponible en: http://www.dspace.unitru.edu.pe/handle/UNITRU/732

  12. Global Initiative for Asthma 2018. Global Strategy for Asthma Management and Prevention. Lausanne, Switzerland: Eur Respiratory Soc; 2018 [acceso 15/11/2019]. Disponible en: http://www.ginasthma.org

  13. Global Initiative for asthma. Difficult to treat & severe asthma in adolescente and adult patients. GINA pocket guide for health professionals. Lausanne, Switzerland: Eur Respiratory Soc; 2018 [acceso 15/11/2019]. Disponible en: http://www.ginasthma.org

  14. Cárdenas-Contreras R. Estudio de fenotipos clínicos asociados a asma refractaria [tesis]. Madrid: Universidad Complutense de Madrid; 2015 [acceso 25/09/2020]. Disponible en: http://www.eprints.ucm.es

  15. Lezana-Soya V, Navia-Lezana V, Puchi-Silva A. Obesidad infantil y asma bronquial. Neumol Pediatr.2019;14 (4):200-4.

  16. Pineda-Montes LM. Crisis de Asma Bronquial y Obesidad en niños de 3 a 14 años, en el Hospital Nacional Docente Madre Niño San Bartolomé, enero-octubre de 2015 [tesis]. Lima, Perú: Universidad Ricardo Palma; 2016 [acceso 15/09/2020]. Disponible en: http://www.repositorio.urp.edu.pe/bitstream/handle/urp/721/Pineda_l.pdf?sequence=1&isAllowed=y

  17. Basain-Valdés JM, Valdés-Alonso MC, Pérez Martínez M, Jorge-Díaz MA, Linares-Valdés H. Papel de la leptina como señal aferente en la regulación de la homeostasis energética. Rev Cubana Pediatr. 2016 [acceso 15/09/2020];88(1). Disponible en: http://www.revpediatria.sld.cu/index.php/ped/article/view/179/56

  18. Esquivel-Lauzurique M. Crecimiento y desarrollo. En: Prieto D, editor. Pediatría. Diagnóstico y tratamiento. La Habana: Editorial Ciencias Médicas; 2016. p. 18-29.

  19. GINA Executive Committee. Global Strategy for Asthma Management and Prevention. Lausanne, Switzerland: Eur Respiratory Soc; 2007 [acceso 15/09/2020]. Disponible en: http://www.ginasthma.org

  20. Nasiff-Hadad A, Pérez-Pérez LM. Primer Consenso Nacional de dislipoproteinemias: Guía para la prevención, detección, diagnóstico y tratamiento. La Habana: Editorial Ciencias Médicas; 2005.

  21. Araujo O, Carbajal F. Diabetes mellitus de tipo I en el niño y adolescente. En: Prieto D, editor. Pediatría. Diagnóstico y tratamiento. La Habana: Editorial Ciencias Médicas; 2016. p. 374-8.

  22. Ross KR, Hart MA. Assessing the relationship between obesity and asthma in adolescent patients: a review. Adolesc Health, Med Ther. 2013;4:39-49. doi: http://dx.doi.org/10.2147/AHMT.S26707

  23. Peralta G, Fuertes E, Granell R, Mahmoud O, Roda C, Serra I, et al. Childhood Body Composition Trajectories and Adolescent Lung Function. Findings from the ALSPAC study. Am J Respirator Crit Care Med. 2019;200(1). doi: https://doi.org/10.1164/rccm.201806-1168OC

  24. Lang JE, Holbrook JT, Wise RA, Dixon AE, Teague WG, Wei CY. Obesity in Children with Poorly Controlled Asthma: Sex Differences. Pediatric Pulmonol. 2013;48:847-56.

  25. Hinojosa-Ticona DJ. El sobrepeso y la obesidad en pacientes pediátricos hospitalizados por crisis asmática en el Hospital Hipólito Unanue De Tacna, 2017-2019 [tesis]. Tacna, Perú: Universidad Nacional Jorge Basadre; 2020 [acceso 20/09/2020]. Disponible en: https://www.repositorio.unjbg.edu.pe

  26. Arshi M, Cardinal J, Hill RJ, Davies PSW, Wainwright C. Asthma and insulin resistance in children. Respirology. 2010;15(5):779-84.

  27. Al-Shawwa BA, Al-Huniti NH, DeMattia L, Gershan W. Asthma and insulin resistance in morbidly obese children and adolescents. J Asthma. 2007;44(6):469-73.

  28. Cottrell L, Neal WA, Ice C, Perez MK, Piedimonte G. Metabolic abnormalities in children with asthma. Am J Respir Crit Care Med. 2011;183(4):441-8.

  29. Del-Rio-Navarro BE, Castro-Rodríguez JA, Garibay Nieto N, et al. Higher metabolic syndrome in obese asthmatic compared to obese nonasthmatic adolescent males. J Asthma. 2010;47(5):501-6.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Rev Cubana Pediatr. 2021;93