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Medicina & Laboratorio

2022, Number 4

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Medicina & Laboratorio 2022; 26 (4)

Pediatric metabolic index in Venezuelan adolescents

Acosta-García E

Language: Spanish
References: 26
Page: 323-333
PDF size: 120.21 Kb.


ABSTRACT

Introduction. The pediatric metabolic index (PMI) is a specific index according to sex and age to predict cardiometabolic alterations in this population. The objective of this study was to assess the PMI in adolescents according to grouped cardiovascular risk factors (CVRF) and its relationship with indicators of adiposity, dyslipidemia, oxidative stress, inflammation, insulin resistance and hypertension in adolescents. Methodology. The study was descriptive, correlational and cross-sectional in 80 adolescents. Glycemia, lipid profile, insulin, ultrasensitive PCR, IL-6, TNF-α, 8-isoprostane and oxidized LDL were determined, and the HOMA-IR index was calculated. The weight, height and waist circumference were measured, and the body mass index, conicity index, waist/height ratio were determined and then the PMI was calculated. Blood pressure, physical activity and smoking levels were also determined. Results. Those who presented three or more CVRF showed higher PMI values than those who presented less risk factors (p‹0.001). In addition, the PMI correlated with indicators of adiposity, blood pressure, lipid profile components, oxidative stress markers and HOMA-IR. Conclusion. The PMI increased as the group of CVRF did, and it was related to the majority of the indicators studied, except for the markers of inflammation and glucose levels. Additionally, the PMI turned out to be an indicator of easy determination and application, which can corroborate or complement the clinical findings that could be detected through the use of anthropometric indicators of daily use in medical practice.


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