medigraphic.com
SPANISH

Revista del Hospital Psiquiátrico de La Habana

ISSN 0138-7103 (Print)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2021, Number 2

<< Back Next >>

Revista del Hospital Psiquiátrico de La Habana 2021; 18 (2)

Neuropsychological evaluation of a case of Wernicke´s aphasia

Cortés CN, Seubert RAN
Full text How to cite this article

Language: Spanish
References: 20
Page:
PDF size: 390.48 Kb.


Key words:

glioblastoma multiforme, neuropsychological evaluation, Wernicke´s aphasia.

ABSTRACT

Introduction: This case illustrates a glioblastoma multiforme that generated aphasia. Although aphasia is usually a sequel of a cerebral vascular event, it has been reported to be present after a tumor lesion; which makes the present case valuable and exemplifies the importance of neuropsychology in oncologic disease.
Objective: To present a clinical case that illustrates how a tumor lesion can cause cognitive symptomatology.
Case presentation: After identifying an intra-axial tumor lesion in the left temporoinsular region by structural MRI, the patient underwent tumor biopsy and resection. A pre-surgical neuropsychological evaluation was requested. From the application of the Barcelona Brief Test, a fluent language with agrammatisms, phonological and literal paraphasias in spontaneous language, repetition and naming, phonological paragraphies, diminished informative content and difficulties in sentence comprehension were identified; suggesting Wernicke's aphasia. An anatomical correlation has been described between a lesion in the posterior superior temporal gyrus and Wernicke's aphasia, as observed in the case. Specifically, the patient presented with Wernicke's aphasia type I and II due to the anatomofunctional correlate and the presence of fluent speech, agrammatisms and paraphasias.
Conclusions: The patient's relatively small oncologic lesion generated a florid and sudden cognitive symptomatology. A neuropsychological evaluation identified the presence of Wernicke's aphasia.


REFERENCES

  1. Olar A, Aldape KD. Using the molecular classification of glioblastoma to inform personalized treatment. J Pathol. 2014;232(2):165-77. PMID: 24114756

  2. Ostrom QT, Gittleman H, Truitt G, Boscia A, Kruchko C, Barnholtz-Sloan JS. CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2011-2015. Neuro Oncol. 2018;20(suppl_4):iv1-iv86. PMID: 30445539

  3. Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007; 114(2): 97-109. PMID: 17618441

  4. Engelhard HH, Villano JL, Porter KR, Stewart AK, Barua M, Barker FG, Newton HB. Clinical presentation, histology, and treatment in 430 patients with primary tumors of the spinal cord, spinal meninges, or cauda equina. J Neurosurg Spine. 2010;13(1):67-77. PMID: 20594020

  5. Rijnen SJM, Butterbrod E, Rutten GM, Sitskoorn MM, Gehring K. Presurgical Identification of Patients with Glioblastoma at Risk for Cognitive Impairment at 3-Month Follow-up. Neurosurg. 2020;87(6):1119–29. PMID: 32470985

  6. Le H, Lui MY. Aphasia. 2021. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2021. PMID: 32644741

  7. De Dios S, Durkin NM, Soble JR. Case of right hemispatial neglect and transcortical sensory aphasia following left occipitotemporoparietal glioblastoma resection. Appl Neuropsychol Adult. 2021;28(1):117-23. PMID: 30987454

  8. Peña J. Programa Integrado de Exploración Neuropsicológica. España: Masson; 1986.

  9. Asociación Médica Mundial (AMM). Declaración de Helsinki de la AMM. Principios éticos para las investigaciones médicas en seres humanos. JAMA.2017;310(20):2191-4. DOI: 10.1001/jama.2013.281053

  10. Peña J. Normalidad, Semiología y Patología Neuropsicológicas. España: Masson; 1991.

  11. Damasio A. Signs of Aphasia. En: Taylor M (ed.) Acquired Aphasia (3.er ed.). EUA, Nueva York: Academic Press; 1998. pp. 25-40.

  12. Ardila A. Las afasias. Guadalajara: Universidad de Guadalajara; 2005.

  13. Lebrun Y. Anosognosia in aphasics. Cortex. 1987;23(2):251-63. PMID: 2440639

  14. Vendrell JM. Las afasias: semiología y tipos clínicos. Rev Neurol. 2001;32(10):980-6. PMID: 11424058

  15. Damasio H. Neuroanatomical Correlates of the Aphasia. En: Taylor M (ed.) Acquired Aphasia (3.er ed.). EUA, Nueva York: Academic Press; 1998. pp. 43-70.

  16. Solanki C, Sadana D, Arimappamagan A, Rao KVLN, Rajeswaran J, Subbakrishna DK, Santosh V, Pandey P.Impairments in Quality of Life and Cognitive Functions in Long-term Survivors of Glioblastoma. J Neurosci Rural Pract. 2017; 8(2):228-35. PMID: 28479798

  17. Gately L, McLachlan SA, Dowling A, Philip J. Life beyond a diagnosis of glioblastoma: a systematic review of the literature. J Cancer Surviv. 2017; 11(4): 447–452. DOI: 10.1007/s11764-017-0602-7

  18. Catt S, Chalmers A, Fallowfield L. Psychosocial and supportive-care needs in high-grade glioma. Lancet Oncol. 2008;9(9):884-91. PMID: 18760244

  19. Malec J. Evaluación para planear la rehabilitación neuropsicológica. En: Moreno G (ed.) Rehabilitación neuropsicológica.Manual Internacional. México, CDMX: Manual Moderno; 2019. pp. 36-48.

  20. Preusser M, de Ribaupierre S, Wöhrer A, Erridge SC, Hegi M, Weller M, et al. Current concepts and management of glioblastoma. Ann Neurol. 2011;70(1):9-21. DOI: 10.1002/ana.22425. PMID: 21786296




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Revista del Hospital Psiquiátrico de La Habana . 2021;18