medigraphic.com
ISSN 1729-6935 (Electronic)
16 de abril

2021, Number 281

<< Back Next >>

16 de abril 2021; 60 (281)

Precision medicine in cancer treatment

Soriano-Lorenzo JL

Language: Spanish
References: 7
Page: 1-2
PDF size: 416.37 Kb.


Text Extraction

Mr. Editor:

Precision medicine is an individualized therapeutic modality that takes into account the genetic variability of patients, the environment in which they live and lifestyles, in order to draw up strategies for the prevention, diagnosis and treatment of diseases.
Cancer is a very heterogeneous disease, characterized by the development and accumulation of genetic alterations in the tumor cell throughout the development of the disease. However, few of these alterations are common; what has been shown with increasing evidence is that, each person expresses their own genetic profile of cancer.


REFERENCES

  1. Pezo RC, Bedard PL. Definitions: Translational and Personalised Medicine, Biomarker and Pharmacodynamics. En: Tortora G, Sessa C, Scarpa A, Banerjee S. ESMO Handbook of Translational Research. 1st. Lugano: ESMO Press; 2015.p. 1-12.

  2. Johnson TM. Perspective on precision medicine in oncology. Pharmacotherapy. [Internet]. 2017 [citado 23/8/2020]; 37(9):988-989. Disponible en: https://doi.org/10.1002/phar.1975.

  3. Prat A, Pineda E, Adamo B, Galvan P, Fernandez A, Gaba L, et al. Clinical implications of the intrinsic molecular subtypes of breast cancer. Breast. [Internet]. 2015 [citado 23/8/2020]; 24(Suppl 2):S26-S35. Disponible en: http://dx.doi.org/10.1016/j.breast.2015.07.008.

  4. Krzyszczyk P, Acevedo A, Davidoff E, Timmins LM, Marrerro Berrios I, Patel M, et al. The growing role of precision and personalized medicine for cancer treatment. Technology (Singap World Sci). [Internet]. 2018 [citado 23/8/2020]; 6(3-4):79-100. Disponible en: https://doi.org/10.1142/S2339547818300020.

  5. Zhang W, Wang J, Menon S. Advancing cancer drug development through precision medicine and innovative designs. J Biopharm Stat. [Internet]. 2018 [citado 23/8/2020]; 28(2):229-244. Disponible en: https://doi.org/10.1080/10543406.2017.1402784.

  6. White NW, Kulasingam V, Diamandis EP, Yousef GM. Tsongalis GJ, Vermeulen L, et al. The use of targeted therapies for precision medicine in oncology. Clin Chem. [Internet]. 2016 [citado 23/8/2020]; 62(12):1556-1564. Disponible en: https://academic.oup.com/clinchem/article-abstract/62/12/1556/5612042

  7. Mazorra Z, Chao L, Lavastida A, Sanchez B, Ramos M, Iznaga N, et al. Nimotuzumab: beyond the EGFR signaling cascade inhibition. Sem Oncol. [Internet]. 2018 [citado 23/8/2020]; 45(1-2):18-26. Disponible en: https://doi.org/10.1053/j.seminoncol.2018.04.008




2020     |     www.medigraphic.com