Diagnosis and treatment of biliary dyskinesia syndrome improve quality of life of patients with dysfunction response syndrome (study REDIS-3) still called dysautonomia

Luis Fernando García-Frade Ruiz; Nadia Giovanna Chía-Vázquez

2022, Number 6

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Med Int Mex 2022; 38 (6)

Diagnosis and treatment of biliary dyskinesia syndrome improve quality of life of patients with dysfunction response syndrome (study REDIS-3) still called dysautonomia

García-Frade Ruiz LF, Chía-Vázquez NG

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Language: Spanish
References: 26
Page: 1178-1192
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ABSTRACT

Objective: To establish more specific and effective treatments for REDIS syndrome.
Materials and Methods: A retrospective study was carried out in which the biliary scintigrams of patients with symptoms of REDIS syndrome sent by our team to a nuclear medicine laboratory were obtained over a period of 9 years to know the frequency of biliary dyskinesia syndrome in this population. Subsequently, the patient files were reviewed to find out the most frequent symptoms. Authorization was requested from the World Health Organization for the use and application of the WHO-QOL BREF quality of life assessment scale, which was sent to postoperative cholecystectomy patients through an electronic form with prior authorization from the patient, and they responded a pre-surgical and a post-surgical scale.
Results: Of 130 patients with REDIS syndrome, 62 obtained a positive result in the nuclear medicine test, which represented 48% of the studied patients, of whom 27 underwent laparoscopic cholecystectomy.
Conclusions: Biliary dyskinesia syndrome seems to accompany a whole group of manifestations present in what is now called primary dysautonomia, which we have proposed to call more specifically REDIS syndrome, in which approximately half of the patients present disorders of the biliary function, in which case, cholecystectomy substantially improves the quality of life of this population.

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