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2023, Number 01

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Revista Médica Sinergia 2023; 8 (01)

Eosinophilic esophagitis: main cause of dysphagia in children and young adults

Rivera SN, Solera VA, Castro QDA
Full text How to cite this article

Language: Spanish
References: 15
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Key words:

Eosinophilic esophagitis, eosinophilia, allergens, dysphagia, endoscopy.

ABSTRACT

Eosinophilic esophagitis is a chronic inflammatory disease of the esophagus that occurs due to an immunoallergic response triggered in most cases by food antigens. Clinically it is characterized by signs and symptoms related to esophageal dysfunction and histologically by tissue inflammation in which eosinophils predominate. Eosinophilic eophagitis is diagnosed when there are symptoms related to esophageal dysfunction such as dysphagia and food impaction, the presence of ≥15 eosinophils per high-power field on esophageal mucosal biopsy, and after a thorough evaluation for disorders that may cause or contribute to esophageal eosinophilia. The treatment consists of dietary modifications, pharmacological therapies and endoscopic interventions. In 2022, dupilumab became the first Food and Drug Administration -approved treatment for eosinophilic esophagitis. The importance of health personnel dealing with this disease lies in the fact that although it is a chronic disease, its early and timely diagnosis improves the evolution of the disease and the quality of life of the patient's treatment.


REFERENCES

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Revista Médica Sinergia. 2023;8