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2022, Number 4

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Dermatología Cosmética, Médica y Quirúrgica 2022; 20 (4)

Superficial basal cell carcinoma: A different approach in diagnostic and treatment

Fernández MM, Rivera LFP, Toussaint CS, Roldán MR
Full text How to cite this article

Language: Spanish
References: 14
Page: 431-435
PDF size: 198.46 Kb.


Key words:

basal cell carcinoma, confocal reflectance microscopy, imiquimod, tretinoin.

ABSTRACT

Basal cell carcinoma (BCC) is the most common malignancy in humans. Its incidence has been increasing, since it is a tumor that derives mainly due to accumulated sun damage on the skin.
Although BCC has low mortality it can cause a significant impact on the quality of life mainly through local destruction. The definitive diagnosis is achieved through a histological study, however, both dermoscopy and confocal reflectance microscopy provide data of relevance for early clinical diagnosis. Despite the high recurrence rate in topical treatments as monotherapy, the combined treatment using topical imiquimod 5% and topical tretinoin 0.05% was found to be effective for the total resolution of superficial BCC.
We present the case of a 74-year-old female with a lesion on the posterior aspect of the trunk, with the diagnosis of superficial BCC, treated with a combination of topical imiquimod and tretinoin.


REFERENCES

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  2. Baladrón A y Pérez L, Aplicación de la dermatoscopia para el diagnósticodel carcinoma basocelular en atención primaria, Formación MédicaContinuada en Atención Primaria 2016; 23(2),e23-5.

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  6. Shahriari N, Grant Kels J, Rabinovitz H, Oliviero M y Scope A, Reflectanceconfocal microscopy, Journal of the American Academy of Dermatology2021; 84(1):1-14.

  7. González S, Sánchez V, González Rodríguez A, Parrado C y UllrichM, Patrones de microscopía confocal para el cáncer cutáneo no melanomay aplicaciones clínicas, Actas Dermo-Sifiliográficas 2014; 105(5):446-58.

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  11. Baldwin HE, Nighland M, Kendall C, Mays DA, Grossman R y NewburgerJ, 40 years of topical tretinoin use in review, Journal of Drugs inDermatology 2013; 12(6):638-42.

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Dermatología Cosmética, Médica y Quirúrgica. 2022;20