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2021, Number 3

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Medicina & Laboratorio 2021; 25 (3)

Immune complex-mediated rapidly progressive glomerulonephritis (type II). Literature review

Nieto-Ríos JF, Giraldo-Serna MB, García-Prada CA, Lotero-Cadavid AF, Serna-Higuita LM, Arias LF
Full text How to cite this article

Language: Spanish
References: 51
Page: 569-580
PDF size: 470.00 Kb.


Key words:

glomerulonephritis, immune complexes, IgA nephropathy, Henoch- Schönlein purpura, end stage renal disease, biopsy, steroids.

ABSTRACT

Rapidly progressive immune complex-mediated glomerulonephritis (RPGNMN II) is a clinical syndrome characterized by severe deterioration of renal function associated with hematuria, edema, and oliguria. It is histologically characterized as a crescentic glomerulonephritis, with the presence of granular deposits on immunofluorescence. Although it is a rare condition, it is a potentially serious disease that may progress to chronic renal disease, therefore its early identification is essential. Here we present a review of this form of glomerulonephritis, with emphasis on its etiology and the currently available therapeutic options.


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