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Órgano Oficial de la Asociación Dental Mexicana

2003, Number 2

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Rev ADM 2003; 60 (2)

Biocompatibility evaluation of portland cement implanted in subepithelial connective tissue in rats

Campos QI, Llamosas HE, Morales de la LR

Language: Spanish
References: 20
Page: 45-51
PDF size: 133.64 Kb.


ABSTRACT

Mineral trioxide aggregate (MTA) has shown, in many studies, to be a sealant material with a high potential. Recently MTA has been related with the Portland cement (PC), basically has the same components; Calcium, Phosphate ans Silica.
The possible use op PC as a dental material has raised great polemics opening new lines of research.
It is known that in order to determine de biocompatibility potential of dental materials, several techniques had been used such as: a) in vitro cellular or tissue citotoxicity test. b) in vivo subcutaneous tissue or osseous implants tissue testing.
Due to the lack of existing information and based in Wucherpfenning studies who mentions several cases with MTA and PC, an experimental prospective and longitudinal study was carried out in order to evaluate the CP biocompatibility, which was included in polypropilene tubes implanted in sub epithelial connective tissue of rats.
For the study 10 Wistar rats were used, 9 were implanted a tube with PC and an empty tube each on either side of the middle line, the last rat was left as a control. The animals were sacrificed at 8, 15, 30, and 45 days after implantation for histological evaluation.
Results showed no difference among groups because the tissue reaction was similiar.
It should be noted that an acute to chronic inflammation was observed, with a notorious presence of mast cells and eosinophils related to an allergic reaction.


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