medigraphic.com
SPANISH

Acta de Otorrinolaringología & Cirugía de Cabeza y Cuello

ISSN 2539-0859 (Electronic)
ISSN 0120-8411 (Print)
Asociación Colombiana de Otorrinolaringología y Cirugía de Cabeza y cuello, Maxilofacial y Estética Facial (ACORL)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2022, Number 3

<< Back Next >>

Acta de Otorrinolaringología CCC 2022; 50 (3)

Characteristics of smell and taste alteration in patients with COVID-19

Chemas-Velez MM, Núñez-Ordoñez N, Téllez PA
Full text How to cite this article

Language: Spanish
References: 20
Page: 194-200
PDF size: 169.37 Kb.


Key words:

Dysgeusia, COVID-19, taste, smell.

ABSTRACT

Introduction: Identifying symptoms or symptom combinations with a high predictive value for diagnosing a disease is a crucial strategy for controlling transmissible diseases. Smell and taste alterations have been identified as highly prevalent symptoms of COVID-19 and have been used as a reliable early predictor of the disease. The objective in this study was characterizing the prevalence of smell and taste alterations in patients with COVID-19 in the Colombian population. Materials and methods: Cross-sectional, descriptive study. A telephonic and electronic survey was applied to adult patients with SARS-CoV-2 infection confirmed by PCR. Results: 182 patients were included. 59% presented with smell alterations and 54% with taste symptoms. Among these patients, 77% and 82% respectively perceived symptomatic improvement. 14% of patients presented smell alterations before the onset of other COVID-19 symptoms. 9% reported smell alterations to be the only symptom of the disease. 8% of patients perceived taste alterations as a first symptom and 6% reported it to be the only symptom of the disease. Conclusion: Taste and smell alterations are highly prevalent symptoms in Colombian patients with Covid-19 and in some cases they can be the either the first or the only perceived symptoms of the disease.


REFERENCES

  1. Coronavirus (COVID-19) Cases - Statistics and Research -Our World in Data [Internet]. [Citado el 08 de mayo de 2021].Disponible en: https://ourworldindata.org/covid-cases

  2. Lechien JR, Chiesa-Estomba CM, de Siati DR, Horoi M, le BonSD, Rodriguez A, et al. Olfactory and gustatory dysfunctionsas a clinical presentation of mild-to-moderate forms of thecoronavirus disease (COVID-19): a multicenter Europeanstudy. Eur Arch Otorhinolaryngol. 2020;277(8):2251-61. doi:10.1007/s00405-020-05965-1.

  3. Menni C, Valdes AM, Freidin MB, Ganesh S, El-SayedMoustafa JS, Visconti A, et al. Loss of smell and taste incombination with other symptoms is a strong predictor ofCOVID-19 infection. medRxiv. 2020.04.05.20048421. doi:10.1101/2020.04.05.20048421.

  4. Tong JY, Wong A, Zhu D, Fastenberg JH, Tham T. The prevalenceof olfactory and gustatory dysfunction in COVID-19 patients:a systematic review and meta-analysis. Otolaryngol Head NeckSurg. 2020;163(1):3-11. doi: 10.1177/0194599820926473.

  5. Yan CH, Faraji F, Prajapati DP, Boone CE, DeConde AS.Association of chemosensory dysfunction and COVID-19 inpatients presenting with influenza-like symptoms. Int ForumAllergy Rhinol. 2020;10(7):806-13. doi: 10.1002/alr.22579.

  6. Hjelmesæth J, Skaare D. Loss of smell or taste as the onlysymptom of COVID-19. Tidsskr Nor Laegeforen. 2020;140(7).doi: 10.4045/tidsskr.20.0287.

  7. Vroegop AV, Eeckels AS, Van Rompaey V, Abeele D, SchiappoliMS, Alobid I, et al. COVID-19 and olfactory dysfunction - anENT perspective to the current COVID-19 pandemic. B-Ent.2020;16(1):81-5. doi: 10.5152/B-ENT.2020.20127.

  8. Vargas-Gandica J, Winter D, Schnippe R, Rodríguez-MoralesAG, Mondragon J, Escalera-Antezana JP, et al. Ageusia andanosmia, a common sign of COVID-19? A case series fromfour countries. J Neurovirol. 2020;26(5):785-9. doi: 10.1007/s13365-020-00875-8.

  9. National Health and Nutrition Examination Survey 2013-2014data documentation, codebook, and frequencies taste & smell(CSQ_H).

  10. Boesveldt S, Postma EM, Boak D, Welge-Luessen A, Schöpf V,Mainland JD, et al. Anosmia-A clinical review. Chem Senses.2017;42(7):513-23. doi: 10.1093/chemse/bjx025.

  11. Young BE, Ong SWX, Kalimuddin S, Low JG, Tan SY,Loh J, et al. Epidemiologic features and clinical course ofpatients infected with SARS-CoV-2 in Singapore. JAMA.2020;323(15):1488-94. doi: 10.1001/jama.2020.3204.

  12. Marchese-Ragona R, Ottaviano G, Piero N, Vianello A, MiryamC. Sudden hyposmia as a prevalent symptom of COVID-19infection. medRxiv. 2020. doi: 10.1101/2020.04.06.20045393.

  13. Sungnak W, Huang N, Bécavin C, Berg M; HCA LungBiological Network. SARS-CoV-2 entry genes are most highlyexpressed in nasal goblet and ciliated cells within humanairways. ArXiv. 2020:arXiv:2003.06122v1. Update in: NatMed. 2020;26(5):681-7.

  14. Kalinke U, Bechmann I, Detje CN. Host strategies against virusentry via the olfactory system. Virulence. 2011;2(4):367-70.doi: 10.4161/viru.2.4.16138.

  15. Brann DH, Tsukahara T, Weinreb C, Lipovsek M, Vanden Berge K, Gong B, et al. Non-neuronal expression ofSARS-CoV-2 entry genes in the olfactory system suggestsmechanisms underlying COVID-19-associated anosmia. SciAdv. 2020;6(31):eabc5801. doi: 10.1126/sciadv.abc5801.

  16. Addison AB, Wong B, Ahmed T, Macchi A, Konstantinidis I,Huart C, et al. Clinical Olfactory Working Group consensusstatement on the treatment of postinfectious olfactorydysfunction. J Allergy Clin Immunol. 2021;147(5):1704-1719.doi: 10.1016/j.jaci.2020.12.641.

  17. Abdelalim AA, Mohamady AA, Elsayed RA, Elawady MA,Ghallab AF. Corticosteroid nasal spray for recovery of smellsensation in COVID-19 patients: A randomized controlledtrial. Am J Otolaryngol. 2021;42(2):102884. doi: 10.1016/j.amjoto.2020.102884.

  18. Hummel T, Reden KRJ, Hähner A, Weidenbecher M,Hüttenbrink KB. Effects of olfactory Training in patients witholfactory loss. Laryngoscope. 2009;119(3):496-9. doi: 10.1002/lary.20101.

  19. Altundag A, Cayonu M, Kayabasoglu G, Salihoglu M, TekeliH, Saglam O, et al. Modified olfactory training in patients withpostinfectious olfactory loss. Laryngoscope. 2015;125(8):1763-6. doi: 10.1002/lary.25245.

  20. Henning H. Der Geruch. johann ambrosius barth verlag. 1916.




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Acta de Otorrinolaringología CCC. 2022;50