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Alergia, Asma e Inmunología Pediátricas

Órgano Oficial del Colegio Mexicano de Alergia, Asma e Inmunología Pediátrica y de la Asociación Latinoamericana de Pediatría
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2022, Number 2

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Alerg Asma Inmunol Pediatr 2022; 31 (2)

Chronic spontaneous urticaria in children: report of two cases

Cerda-Reyes S, Campos-Gutiérrez RI, Castillón-Benavides NK, Maldonado-Hernández JG, Rodríguez-González M
Full text How to cite this article 10.35366/109666

DOI

DOI: 10.35366/109666
URL: https://dx.doi.org/10.35366/109666

Language: Spanish
References: 7
Page: 58-60
PDF size: 137.11 Kb.


Key words:

urticaria, angioedema, endotype.

ABSTRACT

Introduction: urticaria is the presences of itching wheals with or without angioedema and is one frequent reason for seeking medical attention for the pediatric patient. When it lasts for more than six weeks or persists despite treatment, it is classified as chronic urticaria and should be addressed and treated in a systematic way to determine whether it is triggered by inducible elicitors or as chronic spontaneous urticaria (CSU). Cases report: we present two cases of pediatric patients with CSU in whom the approach was performed in a systematic manner until requiring management with the biological agent (omalizumab), after which optimal control was achieved. Conclusions: CSU in the pediatric patient is a clinical entity that must be recognized at all different levels of healthcare to achieve the optimal approach and adequate therapeutic management of patients.


REFERENCES

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  2. Maurer M, Eyerich K, Eyerich S, Ferrer M, Gutermuth J, Hartmann K et al. Urticaria: collegium internationale allergologicum (CIA) update 2020. Int Arch Allergy Immunol. 2020; 181 (5): 321-333. doi: 10.1159/000507218.

  3. Zuberbier T, Abdul Latiff AH, Abuzakouk M, Aquilina S, Asero R, Baker D et al. The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria. Allergy. 2021. doi: 10.1111/all.15090.

  4. Church MK, Kolkhir P, Metz M, Maurer M. The role and relevance of mast cells in urticaria. Immunol Rev. 2018; 282 (1): 232-247. doi: 10.1111/imr.12632.

  5. Asero R, Cugno M. Biomarkers of chronic spontaneous urticaria and their clinical implications. Expert Rev Clin Immunol. 2021; 17 (3): 247-254. doi: 10.1080/1744666X.2021.1882304.

  6. Kolkhir P, Church MK, Weller K, Metz M, Schmetzer O, Maurer M. Autoimmune chronic spontaneous urticaria: What we know and what we do not know. J Allergy Clin Immunol. 2017; 139 (6): 1772-1781.e1. doi: 10.1016/j.jaci.2016.08.050.

  7. Williams P, Kavati A, Pilon D, Xiao Y, Zhdanava M, Balp MM et al. Health care burden and treatment patterns in commercially insured children with chronic idiopathic/spontaneous urticaria: A real-world study in the United States. Allergy Asthma Proc. 2018; 39 (3): 201-211.




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Alerg Asma Inmunol Pediatr. 2022;31