2003, Number 3
Efficacy and safety of bismuth subgalate and salicilate applied as hemostatic agent after third molar extraction
Mora LTA, Trujillo FJJ, Mora SJS
Language: Spanish
References: 8
Page: 90-94
PDF size: 69.26 Kb.
ABSTRACT
The subgallate and subsalicilate of bismuth are substances that had been employed as hemostatic agents, in adenotonsillectomies activating the Hageman Factor in coagulation. Question: Are they safe and efficient hemostatic agents after third molar extractions? Purpose: Evaluate the efficiency and safety as hemostatic agents. Hypothesis: They are safe and efficient agents for the bleeding control after third molar extractions. Justification: There isn’t an efficient, safe, easy to obtain and unexpensive agent to help bleeding control. Study design: Randomized placebo-controlled trial. Method: In patients with indication for surgical extractions of the third molars, subgallate or subsalicilate of bismuth was applied topically randomly in each alveolus and a control substance in the contralateral alveolus. Results: The data were analized with the ANOVA parametric test. Seventy one patient were enrolled. Two hundred and eighty four surgical extraction were performed. Seventy one with each of the substances, each one with its control. The group with subgallate and subsalicillate of bismuth obtain the minor time (1.97 min) and the control group obtained the largest (3.52 min) with a statistically significant diference (F = 146.62; p ‹ 0.05). Conclusion: The subgallate and subsalicilate of bismuth are efficient and safe in the bleeding control without adverse effects.REFERENCES