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Federación Mexicana de Ginecología y Obstetricia, A.C.
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2023, Number 01

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Ginecol Obstet Mex 2023; 91 (01)

Concordance in cytological, colposcopic and histological findings in premalignant lesions of the cervix

Mayorga-Bautista CD, Hidalgo-Martínez SM, Romo-Rodríguez MR, Villareal-Ríos E, Robledo-Abarca OM
Full text How to cite this article

Language: Spanish
References: 11
Page: 32-38
PDF size: 188.97 Kb.


Key words:

Low-grade intraepithelial lesion, High-grade intraepithelial lesion, cervical cancer, cytology, colposcopy, biopsy, concordance index.

ABSTRACT

Objective: To determine the concordance in cytologic, colposcopic and histopathologic findings in premalignant lesions of the uterine cervix.
Materials and Methods: Cross-sectional, retrospective and comparative study, carried out in the dysplasia clinic of the Hospital General Regional 1 of the state of Querétaro, Mexico, from January 1 to December 2020, based on information from the records of women with cytology, colposcopy and histopathology (biopsy) report with low- and high-grade intraepithelial lesion. The statistical analysis plan included confidence intervals for averages and percentages. The weighted Kappa Index was used to determine the level of concordance.
Results: Two hundred and ninety records were analyzed. The mean age of the patients was 36 years, the weighted kappa index was k = 0.41 (95%CI: 0.33-0.53) for cytology and colposcopy with a moderate value (fair). For cytology and biopsy, it was k= 0.33 (95%CI: 0.22-0.49) with a poor value (medium). For colposcopy and biopsy, it was k = 0.61 (95%CI: 0.49-0.72) with a value of good (substantial) agreement.
Conclusions: Between cytology and colposcopy the concordance coefficient was moderate, for cytology and biopsy it was poor, while for colposcopy and biopsy it was a substantial.


REFERENCES

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  2. Gupta SM, Mania PJ. Molecular mechanisms in progressionof HPV-associated cervical carcinogenesis. J Biomed Sci 2019;26 (1): 28. https://doi.org/10.1186/s12929-019-0520-2

  3. Solís JG, Briones TI. Prevalence of intraepithelial lesion incervical screening cytology in a First-level Care Unit. RevMed Inst Mex Seguro Soc 2018; 56 (2): 167-72. http://www.ncbi.nlm.nih.gov/pubmed/29902371

  4. Salvent AT, Romero VK. Correlación cito-colpo-histológicaen lesiones premalignas del cuello uterino en el HospitalBásico Píllaro en Ecuador Salvent Tames. Rev Cub Obstet yGinecol 2017; 43 (3). http://www.revginecobstetricia.sld.cu/index.php/gin/article/view/234/177

  5. Zhang X, Dou Y, Wang M, et al. A retrospective analysis on 1901women with high grade cervical intraepithelial neoplasia bycolposcopic biopsy. Eur J Obstet Gynecol Reprod Biol 2017;217: 53-58. http://dx.doi.org/10.1016/j.ejogrb.2017.07.005

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  9. Domínguez B. Infección por el virus del papiloma humanoen adolescentes y adultas jóvenes. Rev Cubana de Obstety Ginecol 2018; 44 (1): 1-13. http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-600X2018000100017&lng=es&tlng=es.

  10. Medina CO, Reyes LP, Gaytán HD, et al. Concordanciacitocolposcópica con la prueba histopatológica en laidentificación de neoplasias intraepiteliales cervicales.Ginecol Obstet Mex 2022; 90 (4): 323x-330. https://doi.org/10.24245/gom.v90i4.5456

  11. Torres PK, Piña SP, Vallejo RV, et al. Molecular Markers forthe Diagnosis of High-Risk Human Papillomavirus Infectionand Triage of Human Papillomavirus-Positive Women. RevInvestig Clinic 2020; 11; 72 (4). https://doi.org/10.24875/RIC.20000058




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Ginecol Obstet Mex. 2023;91