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2023, Number 1

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Rev Mex Traspl 2023; 12 (1)

Cadaveric liver donor with SARS-CoV-2-positive

Martínez-Navarro M, Sánchez-Ojeda M, López-Falcony R, Soto-Granados O, Enrique-Sánchez J, Luna-López G
Full text How to cite this article 10.35366/110002

DOI

DOI: 10.35366/110002
URL: https://dx.doi.org/10.35366/110002

Language: Spanish
References: 13
Page: 41-44
PDF size: 256.12 Kb.


Key words:

cadaveric donor, COVID-19, SARS-CoV-2, cycle threshold.

ABSTRACT

Coronavirus disease (COVID-19) has caused a negative impact on cadaveric organ donation processes in the world. Medical evidence has suggested evaluating the mortality risk of the recipient and the risk of transmission from the surgical team in the decision to use SARS-CoV-2-positive donors. In this case, we report the process of an asymptomatic SARS-CoV-2-positive cadaveric liver donor for a recipient patient with primary liver failure due to thrombosis of the hepatic artery classified as a transplant emergency. The present case may set a precedent for donation and transplant programs to begin considering asymptomatic SARS-CoV-2-positive donors with a high cycle threshold (Ct), for recipients with high mortality and/or morbidity who can potentially benefit.


REFERENCES

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  2. Romagnoli R, Gruttadauria S, Tisone G et al. Liver transplantation from active COVID-19 donors: a lifesaving opportunity worth grasping? Am J Transplant. 2021; 21 (12): 3919-3925. doi: 10.1111/ajt.16823.

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  4. Eichenberger EM, Kaul DR, Wolfe CR. The pandemic provides a pathway: What we know and what we need to know about using COVID positive donors. Transpl Infect Dis. 2021; 23(5):e13727. doi: 10.1111/tid.13727.

  5. Aburto-Morales JS. La pandemia por SARS-CoV-2 (COVID-19) y el replanteamiento de las estrategias en la actividad de donación y trasplantes. Rev Mex Traspl. 2020; 9 (2): 49-50. doi: 10.35366/95706.

  6. Aburto-Morales JS, Romero-Méndez J, Lucio-García CA et al. México ante la pandemia de COVID-19 (SARS-CoV-2) y las recomendaciones al Subsistema Nacional de Donación y Trasplante. Rev Mex Traspl. 2020; 9 (1): 6-14. doi: 10.35366/94024.

  7. Riley DS, Barber MS, Kienle GS et al. CARE guidelines for case reports: explanation and elaboration document. J Clin Epidemiol. 2017; 89: 218-235. doi: 10.1016/j.jclinepi.2017.04.026.

  8. Ley General de Salud. Art 328. 12 de Julio 2018. Estados Unidos Mexicanos.

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  11. Cubelos FN, Sánchez JMR, Nuevo Guisado MT et al. Valor umbral de ciclo en la COVID-19 en pacientes asintomáticos. SEMERGEN. 2021; 47 (5): 355-356. doi: 10.1016/j.semerg.2021.06.003.

  12. Serrano-Cumplido A, Ruiz Garcia A, Segura-Fragoso A et al. Aplicación del valor umbral del número de ciclos (Ct) de PCR en la COVID-19. SEMERGEN. 2021; 47 (5): 337-341. doi: 10.1016/j.semerg.2021.05.003.

  13. Boan P, Marinelli T, Opdam H. Solid organ transplantation from donors with COVID-19 infection. Transplantation. 2022; 106 (4): 693-695. doi: 10.1097/TP.0000000000004074.




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Rev Mex Traspl. 2023;12