Systemic inflammatory response of COVID-19 and its morphological expression, multiple organ damage

José Domingo Hurtado de Mendoza Amat; Teresita Montero González; Israel Borrajero Martínez; Virginia Capó de Paz; Laura López Marín; Carlos Domínguez Álvarez

2021, Number 3

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Rev Cub Med Mil 2021; 50 (3)

Systemic inflammatory response of COVID-19 and its morphological expression, multiple organ damage

Hurtado de Mendoza AJD, Montero GT, Borrajero MI, Capó PV, López ML, Domínguez ÁC

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The COVID-19 pandemic has been the greatest health, social and economic disaster suffered by humanity since the Second World War, which has been the reason for numerous scientific works, interested in finding a solution to the multiple problems it causes. Among these studies are those related to the reaction produced in the body and especially the systemic inflammatory response (SIR) that it triggers.
In Cuba, for several decades, SIR1 and its morphological expression, identified through autopsy studies, have been studied as multiple organ damage (MOD).2,3 Thanks to the high number of cases studied and their results, introduced and processed by the Automated System for the Registration and Control of Pathological Anatomy (SARCAP), developed in the country since the 1980s.4 RIS is common to numerous causal factors, leading to vital damage to the organism.