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2022, Number 1

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Arch Med 2022; 22 (1)

Assessment of postoperative neurocognitive disorders in clinical studies: a scoping review

Rojas GDF, Restrepo BM, Múnera GT, Amaya AJJ, Barrera AJ, Restrepo BD
Full text How to cite this article

Language: Spanish
References: 29
Page: 145-155
PDF size: 314.25 Kb.


Key words:

Neurocognitive Disorders, Cognitive Dysfunction, Postoperative Cognitive Complications, Postoperative Period.

ABSTRACT

Objective: to analyze the definitions used in clinical studies to measure delayed neurocognitive recovery (dNCR) and postoperative neurocognitive disorder (pNCD). Methods: an exploratory review of the literature. Clinical studies on postoperative neurocognitive disorder published since 2013 in journals indexed in Pubmed or Scopus were included. We critically analyzed the methods for assessing dNCR and pNCD, considering as reference the consensus’s recommendations. Results: we identified 13 studies, four randomized clinical trials, and nine observational studies. Only three of these studies used definitions consistent with the consensus for dNCR or pNCD. The main reasons for non-adherence were the measurement points and the non-exclusion of delirium and other mental disorders as potential cognitive decline causes. Conclusion: despite assuming the nomenclature of perioperative neurocognitive disorders, the studies failed to adhere to the diagnostic criteria and measurement points. We propose developing a Core Outcome Set as a strategy to advance to perform more homogeneous, high-quality, and relevant evidence for clinical decision making.


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