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Revista Cubana de Oftalmología

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2021, Number 3

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Rev Cub Oftal 2021; 34 (3)

Application of platelet-rich plasma in ocular surface diseases

León RY, Pérez PZ, Moreno RM, Hernández FY, Brizuela CY
Full text How to cite this article

Language: Spanish
References: 24
Page: 1-15
PDF size: 400.71 Kb.


Key words:

ocular surface diseases, blood-derived products, platelet-rich plasma.

ABSTRACT

Ocular surface diseases are a group of conditions of different etiologies, symptoms and clinical findings with the common features of developing an inflammatory reaction and damaging the ocular surface. Use of blood-derived products for the treatment of ocular surface disorders has increased in ophthalmic care, since their composition is similar to that of natural tears. With the purpose of presenting cell therapy as a new scientific discipline that could be used in our environment, an automated search was conducted about the topic which included publications from the last five years. The search was performed on the Infomed platform, and the information obtained was summarized into a final report stating that blood-derived eye drops provide effective and safe treatment strategies for patients with ophthalmic conditions. Platelet-rich plasma eye drops are a potentially successful treatment option for many ocular surface disorders. However, further studies are required to establish the safety and effectiveness of this type of therapy.


REFERENCES

  1. Fine BS, Yanoff M. Ocular Histology. Hagerstown: Harper and Row Publisher; 1979.

  2. Mishima S, Gasset A, Klyce SD Jr, Baum JL. Determination of tear volume and tear flow. Invest Ophthalmol. 1966 [acceso: 15/06/2021];5:264-76. Disponible en: https://pubmed.ncbi.nlm.nih.gov/5947945/

  3. Riestra AC, Alonso-Herreros JM, Merayo-Lloves J. Plasma rico en plaquetas en superficie ocular. Arch Soc Esp Oftalmol. 2016;91(10):475-90. DOI: https://doi.org/10.1016/j.oftal.2016.03.001

  4. Merayo-Lloves J, Sánchez RM, Riestra AC, Anitua E, Begoña L, Orive G, et al. Autologous Plasma Rich in Growth Factors Eyedrops in Refractory Cases of Ocular Surface Disorders. Ophthalmic Res. 2015;55(2):53-61. DOI: https://doi.org/10.1159/000439280

  5. Freire V. Derivados hemáticos en la regeneración del epitelio corneal: Estudio comparativo in vitro e in vivo [Tesis doctoral]. Leioa: Universidad del País Vasco, Facultad de Medicina y Odontología; 2016 [acceso: 30/06/2021]. Disponible en: https://addi.ehu.es/bitstream/handle/10810/19638/TESIS_FREIRE_VALLEJO_VANESA.pdf?sequence=1

  6. Giannaccare G, Versura P, Buzzi M, Primavera L, Pellegrini M, Campos EC. Blood derived eye drops for the treatment of cornea and ocular surface diseases. Transfus Apher Sci. 2017;56(4):595-604. DOI: https://doi.org/10.1016/j.transci.2017.07.023

  7. Sánchez-Ávila RM, Merayo-Lloves J, Riestra AC, Anitua E, Muruzábal F, Orive G, et al. The Effect of Immunologically Safe Plasma Rich in Growth Factor Eye Drops in Patients with Sjogren Syndrome. J Ocul Pharmacol Ther. 2017;33(5):391-9. DOI: https://doi.org/10.1089/jop.2016.0166

  8. González Iglesias AI, Fernández Delgado N, Forrellat Barrios M, Hernández Ramírez P. Caracterización de los concentrados plaquetarios utilizados en Medicina Regenerativa. Rev Cubana Hematol Inmunol Hemoter. 2017 [acceso: 30/06/2021];30(2):171-8. Disponible en: https://www.researchgate.net/publication/264428478

  9. Merayo-Lloves J, Sánchez-Ávila RM, Riestra AC, Anitua E, Begoña L, Orive G, et al. Safety and Efficacy of Autologous Plasma Rich in Growth Factors Eye Drops for the Treatment of Evaporative Dry Eye. Ophthalmic Res. 2016;56(2):68-73. DOI: https://doi.org/10.1159/000444496

  10. Barría N, Haro F, Henríquez E, Unda M. Concentrados plaquetarios y usos en oftalmología. Rev Med Hum. 2017 [acceso: 30/06/2021]. Disponible en: http://www.medicinayhumanidades.cl/ediciones/2017/especial_oftalmologia/04_CONCENTRADOS%20PLAQUETARIOS.pdf

  11. Anitua E, Muruzabal F, Pino A, Merayo Lloves J, Orive G. Biological stability of plasma rich in growth factors eye drops after storage of 3 months. Córnea. 2018;32(10):1380-6. DOI: https://doi.org/10.1159/000444496

  12. Anitua E, Muruzabal F, Tayebba A, et al. Autologous serum and plasma rich in growth factors in ophthalmology: preclinical and clinical studies. Acta Ophthalmol. 2015;93(8):605-14. DOI: https://doi.org/10.1111/aos.12710

  13. Monzón LC, Cáceres YN. Plasma rico en plaquetas: una alternativa terapéutica versátil en enfermedades oftálmicas. Medic Electr. 2017 [acceso: 30/06/2021];21(2):77-80. Disponible en: https://www.semanticscholar.org/paper/

  14. Anitua E, de la Fuente M, Muruzabal F, Riestra A, Merayo-Lloves J, Orive G. Plasma rich in growth factors (PRGF) eye drops stimulates scarless regeneration compared to autologous serum in the ocular surface stromal fibroblasts. Exp Eye Res. 2015 [acceso: 30/06/2021];135:118-26. DOI: https://doi.org/10.1016/j.exer.2015.02.016

  15. García Conca V. Eficacia y seguridad del plasma rico en plaquetas sobre la superficie ocular y la osmolaridad lagrimal en la enfermedad del ojo seco hiposecretor [Tesis]. España: Universidad Miguel Hernández; 2017.

  16. Ciurtin C, Ostas A, Cojocaru VM, Walsh SB, Isenberg DA. Advances in the treatment of ocular dryness associated with Sjogrens syndrome. Semin Arthritis Rheum. 2015;45:321-7. DOI: https://doi.org/10.1016/j.semarthrit.2015.06.007

  17. Moreno R. Plasma rico en plaquetas: actualización de los sistemas empleados para su obtención. Farm Hosp. 2016;40(5):385-93. DOI: https://dx.doi.org/10.7399/fh.2016.40.5.10561

  18. Soni NG, Jeng BH. Blood-derived topical therapy for ocular surface diseases. Br J Ophthalmol. 2016;100(1):22-7. DOI: https://doi.org/10.1136/bjophthalmol-2015-306842

  19. Anitua E, de la Fuente M, Riestra A, Merayo-Lloves J, Muruzábal F, Orive G. Preservation of Biological Activity of Plasma and Platelet-Derived Eye Drops After Their Different Time and Temperature Conditions of Storage. Cornea. 2015;34(9):11448. DOI: https://doi.org/10.1097/ICO.0000000000000489

  20. Anitua E, Prado R, Orive G. Closing regulatory gaps: new ground rules for platelet-rich plasma. Trends Biotechnol. 2015;33(9):492-5. DOI: https://doi.org/10.1016/j.tibtech.2015.07.002

  21. Akpek EK, Amescua G, Farid M, García-Ferrer FJ, Lin A, Rhee MK, et al. Dry Eye Syndrome Preferred Practice Pattern(R). Ophthalmology. 2019;126(1):286-334. DOI: https://doi.org/10.1016/j.ophtha.2018.10.023

  22. Guijarro Hernández L. Evaluación de la eficacia del empleo de colirio de suero autólogo vs. heterólogo en síndrome de ojo seco [Tesis]: Universidad de Málaga; 2015.

  23. Muñoz CWR, Luna MI, Vázquez ML, García CK, Martínez PM. Aplicación de plasma rico en plaquetas combinado con injerto de membrana amniótica en el tratamiento de adelgazamiento corneal. Rev Mex Oftalmol. 2013 [acceso: 30/06/2021];87(3):158-64. Disponible en: https://www.elsevier.es/es-revista-revista-mexicana-oftalmologia-321

  24. Arnalich F, Rodríguez AE, Luque Río A, Alió JL. Solid Platelet Rich Plasma in Corneal Surgery. Ophthalmol Ther. 2016 [acceso: 20/01/2017];5(1):100-5. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909678/




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Rev Cub Oftal. 2021;34