medigraphic.com
Organo Oficial de la Sociedad Mexicana de Urología

2023, Number 1

<< Back

Rev Mex Urol 2023; 83 (1)

Penile cancer an unnoticed pathology: report of 6 cases

Escobar-Pabón G, Calderón Juan-Martín, Orozco-Delgado D, Vallejo-Suárez C, Chininin-Moreno D, Vaca-Salazar J, Escobar-Estrada D

Language: Spanish
References: 15
Page:
PDF size: 322.14 Kb.


ABSTRACT

Objective: To describe 6 cases of penile cancer and examine their surgical management in a tertiary level hospital.
Methods: Retrospective and descriptive study of penile cancer cases from april 2020 to may 2022 at the Hospital de Especialidades Eugenio Espejo in the city of Quito. Only cases with complete clinical history, confirmatory histopathological diagnosis and post-surgical controls were included.
Results: We describe 6 patients with penile cancer with an average age of 69 years. In the histopathological study, five patients were diagnosed with squamous cell carcinoma and one with nodular melanoma. The most frequent location was on the glans penis in four individuals. According to TNM classification, two patients were stratified as T3Nx, one as T3N1, one as T3N2, one as T4 and one as T4bN3b. In half of the cases, the treatment of choice was total penectomy plus bilateral inguinal lymphadenectomy.
Conclusions: Although penile cancer is a rare pathology, the identification of risk factors and primary lesions can help in the early diagnosis of cancer, thus avoiding metastasis to structures adnexal to the penis and consequent penectomies.


REFERENCES

  1. Douglawi A, Masterson TA. Penile cancerepidemiology and risk factors: A contemporaryreview. Curr Opin Urol. 2019 Mar1;29(2):145–9. DOI: https://doi.org/10.1097/MOU.0000000000000581

  2. Marchioni M, Berardinelli F, De Nunzio C,Spiess P, Porpiglia F, Schips L, et al. Newinsight in penile cancer. Minerva Urol eNefrol. 2018;70(6):559–69. DOI: https://doi.org/10.23736/S0393-2249.18.03215-0

  3. Thomas A, Necchi A, Muneer A, Tobias-Machado M, Tran ATH, Van Rompuy AS, etal. Penile cancer. Nat Rev Dis Prim. 2021;7(1).DOI: https://doi.org/10.1038/s41572-021-00246-5

  4. Ahmed ME, Khalil MI, Kamel MH, Karnes RJ,Spiess PE. Progress on Management of PenileCancer in 2020. Curr Treat Options Oncol.2021;22(0). DOI: https://doi.org/10.1007/s11864-020-00802-3

  5. Hakenberg OW, Dräger DL, Erbersdobler A,Naumann CM, Jünemann KP, Protzel C. TheDiagnosis and Treatment of Penile Cancer. DtschArztebl Int. 2018 Sep 28;115(39):646. DOI:https://doi.org/10.3238/arztebl.2018.0646

  6. Cardona CEM, García-Perdomo HA. Incidenceof penile cancer worldwide: systematic reviewand meta-analysis. Rev Panam Salud Pública.2018 Apr 12;41:e117. DOI: https://doi.org/10.26633/RPSP.2017.117.

  7. Bandini M, Ahmed M, Basile G, Watkin N,Master V, Zhu Y, et al. A global approach toimproving penile cancer care. Nat Rev Urol. 2021Dec 22;1–9. DOI: https://doi.org/10.1038/s41585-021-00557-y

  8. Cabrera-Mora NA, Sánchez-Núñez JE,Hernández-Hernández RA, Rodríguez-ValleED, De los Santos-González JA, Rosas-NavaJE, et al. Clinical and pathologic characteristicsof penile cancer: Current experience at atertiary care hospital center in Mexico. RevMex Urol. 2020;80(5):1–9. DOI: https://doi.org/10.48193/revistamexicanadeurologa.v80i5.679

  9. Vuichoud C, Klap J, Loughlin KR. The EmergingRole and Promise of Biomarkers in Penile Cancer.Urol Clin North Am. 2016;43(1):135–43. DOI:https://doi.org/10.1016/j.ucl.2015.08.012

  10. Hakenberg OW, Compérat EM, MinhasS, Necchi A, Protzel C, Watkin N. EAUguidelines on penile cancer: 2014 update. EurUrol. 2015;67(1):142–50. DOI: https://doi.org/10.1016/j.eururo.2014.10.017

  11. Sánchez-Bermeo AF, Martínez-CarrilloG, Torres-Aguilar J, Bernal-Hernández J.Penectomía parcial como tratamiento parael cáncer de pene localizado, Hospital Juárezde México. Rev Mex Urol. 2016;76(3):182–8. DOI: http://dx.doi.org/10.1016/j.uromx.2016.01.009

  12. Ferrándiz-pulido C, de Torres I, García-patosV. Carcinoma escamoso de pene. Actas Dermosfilogáficas.2012;103(6):478–87. DOI: https://doi.org/10.1016/j.ad.2011.08.008

  13. May A, Joshi P, Davaro F, Raza SJ, SiddiquiS, Hamilton Z. Trends in treatment of cT1penile cancer: Analysis of the National CancerDatabase. Urol Oncol. 2020 Aug 1;38(8):688.e1-688.e9. DOI: https://doi.org/10.1016/j.urolonc.2020.04.013

  14. Teh J, Duncan C, Qu L, Guerra G, NarasimhanV, Pham T, et al. Inguinal lymph node dissectionfor penile cancer: A contemporary review. Vol.9, Translational Andrology and Urology. AMEPublications; 2020. p. 3210–8. DOI: https://doi.org/10.21037/tau.2019.08.37

  15. Niyogi D, Noronha J, Pal M, Bakshi G, PrakashG. Management of clinically node-negativegroin in patients with penile cancer. IndianJ Urol. 2020 Jan 1;36(1):8. DOI: https://doi.org/10.4103/iju.IJU_221_19




2020     |     www.medigraphic.com