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Colegio de Medicina Interna de México.

2023, Number 1

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Med Int Mex 2023; 39 (1)

Linear oral lesions are an early sign of vitamin B12 deficiency

Aranda-Romo S, Aguilar-Zapata FJ, Tejeda-Nava FJ, Dos Santos-Silva AR, Aragón-Martínez OH, Cepeda-Bravo JA

Language: Spanish
References: 11
Page: 178-183
PDF size: 245.44 Kb.


ABSTRACT

Background: Linear oral erythematous lesions are considered early signs of vitamin B12 deficiency; establishing an opportune diagnosis avoids neurological sequelae.
Clinical case: A 60-year-old male patient with type 2 diabetes mellitus in control with metformin for 6 years, who presented burning and pain in the oral cavity of 6 months of evolution, multi-treated without improvement to the indicated therapies. Linear oral erythematous lesions were identified in different areas of the buccal mucosa, a diagnosis of vitamin B12 deficiency was established, without megaloblastic anemia. Two years after his follow-up, he was free of lesions and type 2 diabetes mellitus under control.
Conclusions: Linear erythematous oral lesions on the buccal mucosa are an early sign of vitamin B12 deficiency in patients with diabetes mellitus 2 receiving metformin treatment for prolonged periods.


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