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2023, Number 1

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Med Int Mex 2023; 39 (1)

Adult Still’s disease diagnosed late

Masias-León Y, García DF, Ruíz-González CE, Criado-Villamizar JD, Centeno-Hurtado K, Badillo-Abril R
Full text How to cite this article

Language: Spanish
References: 7
Page: 213-218
PDF size: 229.99 Kb.


Key words:

Adult Still’s disease, Inflammation, Arthritis, Fever of unknown origin.

ABSTRACT

Background: Adult Still’s disease is a rare inflammatory rheumatic illness, with a clinical picture that is difficult to diagnose because it does not have pathognomonic characteristics and the large number of differential diagnoses that present with a similar clinical picture. Added to this is the lack of specific diagnostic tools for this disease.
Clinical case: A 19-year-old female patient, migrant, with Still’s disease of late diagnosis and complications from prolonged corticosteroid therapy.
Conclusions: Adult Still’s disease is a rare and difficult to diagnose disease. Clinical judgment is important when making an early approach that allows the establishment of pharmacological therapies aimed at avoiding disease progression and systemic affectations.


REFERENCES

  1. Meng-Yan Wang, Jin-Chao Jia, Cheng-De Yang, Qiong-Yi Hu. Pathogenesis, disease course, and prognosis ofadult-onset Still’s disease: an update and review. ChinMed J (Engl) 2019; 132 (23): 2856-64. doi: 10.1097/CM9.0000000000000538.

  2. Giacomelli R, Ruscitti P, Shoenfeld Y. A comprehensivereview on adult onset Still’s disease. J Autoimmun 2018;93: 24-36. doi: 10.1016/j.jaut.2018.07.018.

  3. Mitrovic S, Fautrel B. Complications of adult-onset Still’s diseaseand their management. Expert Rev Clin Immunol 2018;14 (5): 351-65. doi: 10.1080/1744666X.2018.1465821.

  4. Jia J, Shi H, Liu M, Liu T, Gu J, Wan L, et al. Cytomegalovirusinfection may trigger adult-onset Still’s disease onset orrelapses. Front Immunol 2019; 898 (10): 1-10. doi: 10.3389/fimmu.2019.00898.

  5. Lee JS, Do IN, Kang DH, et al. Adult onset Still’s disease asa cause of acute severe mitral and aortic regurgitation.Korean J Intern Med 2005; 20 (3): 264-67. doi: 10.3904/kjim.2005.20.3.264.

  6. Patel S, Monemian S, Khalid A, Dosik H. Iron deficiencyanemia in adult onset Still’s disease with a serum ferritinof 26,387 μg/L. Anemia 2011; 2011: 184748. doi:10.1155/2011/184748.

  7. Sfriso P, Bindoli S, Galozzi P. Adult-onset Still’s disease:Molecular pathophysiology and therapeutic advances.Drugs 2018; 78 (12): 1187-1195. doi: 10.1007/s40265-018-0956-9.




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Med Int Mex. 2023;39