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2023, Number 2

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Rev ADM 2023; 80 (2)

Effects of micro-vibration and estrogen on bone: a systematic review.

González RM, Villanueva ARE, García LS, Molina-Frechero N, Salgado MY
Full text How to cite this article 10.35366/110651

DOI

DOI: 10.35366/110651
URL: https://dx.doi.org/10.35366/110651

Language: Spanish
References: 31
Page: 104-114
PDF size: 269.31 Kb.


Key words:

estrogen, mice, bone remodeling, micro vibration, vibration, mechanical loading.

ABSTRACT

Introduction: Bone loss is an event that affects the entire skeleton. Thus, musculoskeletal disorders affect millions of people worldwide and are among the most common causes of chronic pain. Objective: to know the effects of micro-vibration and estrogen on bone remodelling. Material and methods: a systematic review was carried out; seven databases were searched; Controlled clinical studies conducted with rats or mice in the publication period from 2004 to 2022 were included. The quality of the synthesized evidence was assessed using the Jadad scale. Results: fifteen articles were identified as primary studies. Micro vibration reported in vivo/in vitro changes dependent on the stimulus that entails an increase in the outer cortex. In turn, with the administration of estrogen, effects were reported, specifically in the trabecular bone and in the periosteum, as well as immature collagen that indicates bone turnover. Conclusion: both micro-vibration and the administration of estrogen contribute to the remodelling of bone tissue and are usable as a treatment for bone loss.


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Rev ADM. 2023;80