Monteagudo ACJ, Monteagudo GLA, González VK, Chamizo CMG

Language: Spanish
References: 6
Page: 779-785
PDF size: 583.87 Kb.

ABSTRACT

Bowen's disease is a squamous cell carcinoma in situ that affects both skin and mucosa and may progress to invasive squamous cell carcinoma. It is clinically characterized by a well-defined, slow-growing erythematous plaque with irregular, well-demarcated borders and overlying scales or crusts. The clinical presentation is confirmed by histopathological data showing squamous cell carcinoma in situ. We present a 35-year-old male patient with a skin lesion on the right hemithorax of 3 years of evolution. On dermatological examination he presented a single erythematous plaque lesion located on the right hemithorax, with well-defined borders, 2x2 cm in diameter, annular shape and fine scales on the surface. The perilesional skin showed chronic actinic damage. Exeresis and biopsy of the lesion were performed. The biopsy results reported that the histological appearance was consistent with squamous cell carcinoma in situ (Bowen's disease).

REFERENCES

1. Duncan KO, Geisse JK, Leffell DJ. Lesiones epiteliales precancerosas. En: Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, Wolff K. Fitzpatrick. Dermatología en Medicina General. Vol. 1. 8.a ed. Buenos Aires: Médica Panamericana; 2014. p. 1261-82.

2. Caca-Biljanovska N, Arsovska-Bezhoska I, V'lckova-Laskosk M. Giant Bowen's disease on the face: case report and review of the literature. J Med Sciences [internet]. 2019 [citado 7 dic. 2020];7(4):[aprox. 4 p.]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420943/pdf/OAMJMS-7-606.pdf

3. Soyer HP, Rigel DS, Mc Meniman E. Queratosis actínica, carcinoma basocelular y carcinoma epidermoide. En: Bolognia JL, Schaffer JV, Cerroni L. Dermatología. 4.a ed. Barcelona: Elsevier; 2018. p. 3269-3308.

4. James WD, Elston DM, Berger TG. Epidermical nevi, neoplasms and cystic. En: Andrews Diseases of the skin. Clinical Dermatology. 12th ed. Philadelphia: Elsevier; 2016. p. 625-79.

5. Arenas Guzmán R. Enfermedad de Bowen o neoplasia intraepidérmica. En: Dermatología. Atlas, diagnóstico y tratamiento. 6.a ed. [internet]. México: Mc Graw Hill; 2015 [citado 7 dic. 2020]. Disponible en: https://accessmedicina.mhmedical.com/book.aspx?bookid=1538

6. Scalvenzi M, Villani A, Mazzella C, Fabbrocini G, Costa C. Cutaneous Bowen's disease: an analysis of 182 cases according to age, sex, and anatomical site from an Italian center. J Med Sci [internet]. 2019 [citado 7 dic. 2020];7(4):[aprox. 5 p.]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420931/pdf/OAMJMS-7-696.pdf