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2022, Number 1

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Folia 2022; 16 (1)

Liquid nitrogen in the treatment of patients with alopecia areata of the scalp

Sánchez LV, Nieda RL, Martínez FB, Brito GE, Bandomo GNE
Full text How to cite this article

Language: Spanish
References: 9
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PDF size: 281.42 Kb.


Key words:

alopecia areata, cryotherapy, liquid nitrogen.

ABSTRACT

Introduction: The use of cryotherapy with liquid nitrogen in the treatment of alopecia areata of the scalp produces an initial vasoconstriction and then local vasodilatation during the thaw that causes deep massaging in the area of application, and the vessels dilate around the hair follicles area, increasing blood flow which leads to hair regrowth and influencing as immunomodulator.
Objective: To evaluate the results of the application of cryotherapy with liquid nitrogen in patients with alopecia areata of the scalp.
Methods: An observational, descriptive and longitudinal study was carried out at the City Center Community Clinic, in Sancti Spíritus, Cuba, from January 2018 to February 2021. The main variables were plaque repopulation and the presence of adverse events. The sample was made up of 32 patients.
Results: The female sex predominated in 62.15%, the average age was 23.5 years, and the most frequent clinical form was multifocal in 56.2%. At the end of the treatment, 75% of the patients repopulated the alopecic plaques and pruritus was the principal adverse event in 12.5% of the cases.
Conclusions: The response to treatment was favorable in most of the subjects treated with cryotherapy, when repopulating the plaque, totally or partially. Liquid nitrogen cryotherapy proved to be effective and safe in most of the patients treated.


REFERENCES

  1. Dainichi T, Kabashima K. Alopecia areata: What’s new in epidemiology, pathogenesis, diagnosis and therapeutic options? Journal of Dermatological Science. 2017;86:3-12. DOI: http://dx.doi.org/10.1016/j.jdermsci.2016.10.004

  2. González Hernández WC, Méndez Juárez A, Sánchez Álvarez I. Tratamientos emergentes de la alopecia areata. Dermatol Rev Mex. 2019;63(5):469-80.

  3. Restrepo R, Niño LM. Alopecia areata, nuevos hallazgos en histopatología y fisiopatología. Rev Asoc Colomb Dermatol. 2012;20(1):41-53.

  4. Juárez Rendón KJ, Rivera Sánchez G, Reyes López MA. Alopecia areata. Actualidad y perspectivas. Arch Argent Pediatr. 2017;115(6):404-11. DOI: http://dx.doi.org/10.5546/aap.2017.eng.e404

  5. Madani H, Shapiro J. Alopecia areata update. J Am Acad Dermatol. 2000;42(4). DOI: http://dx.doi.org/10.1067/mjd.2000.103909

  6. Gita F, Mohammadreza R. Liquid nitrogen cryotherapy vs. Betamethasone lotion in the management of Alopecia areata. Journal of Clinical Medicine and Research. 2013;5(2):18-22. DOI: https://doi.org/10.5897/JCMR11.041

  7. Kadakia KC, Rozell SA, Butala AA, Loprinzi CHL. Supportive Cryotherapy: A Review From Head to Toe. Journal of Pain and Symptom Management. 2013;47(6). DOI: http://dx.doi.org/10.1016/j.jpainsymman.2013.07.014

  8. Jun M, Lee WS. Therapeutic Effect of Superficial Cryotherapy on Alopecia Areata: A Prospective, Split-scalp Study in Patients with Multiple Alopecia Patches. Ann Dermatol. 2017;29(6). DOI: https://doi.org/10.5021/ad.2017.29.6.722

  9. Zawar VP, Karad GM. Liquid Nitrogen Cryotherapy in Recalcitrant Alopecia Areata: A Study of 11 Patients. Int J Trichology. 2016;8(1):15-20. DOI: https://doi.org/10.4103/0974-7753.179403




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Folia. 2022;16